Evidence map›Paper›PMID 38899440›Full record

ArticleDrug delivery2024

γ-Cyclodextrin hydrogel for the sustained release of josamycin for potential ocular application.

Jennifer Huling, Stefan Oschatz, Helge Lange, Katharina Anna Sterenczak, Thomas Stahnke, Jana Markhoff, Oliver Stachs, Steffen Möller, Nasrullah Undre, Anita Peil and 4 more

Abstract read
In one paragraph

Article in Drug delivery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jennifer HulingInstitute for Biomedical Engineering, Rostock University Medical Center, Rostock, Germany.
Stefan OschatzInstitute for Biomedical Engineering, Rostock University Medical Center, Rostock, Germany.
Helge LangeInstitute for Biomedical Engineering, Rostock University Medical Center, Rostock, Germany.
Katharina Anna SterenczakDepartment of Ophthalmology, Rostock University Medical Center, Rostock, Germany.
Thomas StahnkeDepartment of Ophthalmology, Rostock University Medical Center, Rostock, Germany.
Jana MarkhoffInstitute for Biomedical Engineering, Rostock University Medical Center, Rostock, Germany.
Oliver StachsDepartment of Ophthalmology, Rostock University Medical Center, Rostock, Germany.
Steffen MöllerInstitute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Rostock, Germany.
Nasrullah UndreInstitute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Rostock, Germany.
Anita PeilInstitute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Rostock, Germany.
Anselm JünemannDepartment of Ophthalmology, Rostock University Medical Center, Rostock, Germany.
Niels GrabowInstitute for Biomedical Engineering, Rostock University Medical Center, Rostock, Germany.
Georg FuellenInstitute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Rostock, Germany.
Thomas EicknerInstitute for Biomedical Engineering, Rostock University Medical Center, Rostock, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glaucoma is the leading cause of blindness worldwide. However, its surgical treatment, in particular via trabeculectomy, can be complicated by fibrosis. In current clinical practice, application of the drug, Mitomycin C, prevents or delays fibrosis, but can lead to additional side effects, such as bleb leakage and hypotony. Previous

Indexed as

Delayed-Action Preparationsgamma-CyclodextrinsHydrogelsSolubilityAnimalsAnti-Bacterial AgentsCross-Linking ReagentsDrug CarriersDrug Delivery SystemsDrug LiberationGlaucomaHumansAnti-Bacterial AgentsCross-Linking ReagentsDelayed-Action PreparationsDrug Carriersgamma-cyclodextringamma-CyclodextrinsHydrogelsdrug deliveryfibrosisglaucomahydrogeljosamycinγ-cyclodextrin

Identifiers

PMID38899440
PMCPMC11191840

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.