Evidence map›Paper›PMID 38902245›Full record

ArticleTranslational psychiatry2024

Quantitative MRI at 7-Tesla reveals novel frontocortical myeloarchitecture anomalies in major depressive disorder.

Jurjen Heij, Wietske van der Zwaag, Tomas Knapen, Matthan W A Caan, Birte Forstman, Dick J Veltman, Guido van Wingen, Moji Aghajani

Abstract read
In one paragraph

Article in Translational psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jurjen HeijSpinoza Centre for Neuroimaging, Amsterdam, The Netherlands.
Wietske van der ZwaagSpinoza Centre for Neuroimaging, Amsterdam, The Netherlands.
Tomas KnapenSpinoza Centre for Neuroimaging, Amsterdam, The Netherlands.
Matthan W A CaanDepartment of Biomedical Engineering and Physics, Amsterdam UMC, Location University of Amsterdam, Amsterdam, The Netherlands.
Birte ForstmanDepartment of Brain & Cognition, University of Amsterdam, Amsterdam, The Netherlands.
Dick J VeltmanDepartment of Psychiatry, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Guido van WingenDepartment of Psychiatry, Amsterdam UMC, Location University of Amsterdam, Amsterdam, The Netherlands.
Moji AghajaniDepartment of Psychiatry, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. m.aghajani@fsw.leidenuniv.nl.ORCID 0000-0003-2040-4881

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whereas meta-analytical data highlight abnormal frontocortical macrostructure (thickness/surface area/volume) in Major Depressive Disorder (MDD), the underlying microstructural processes remain uncharted, due to the use of conventional MRI scanners and acquisition techniques. We uniquely combined Ultra-High Field MRI at 7.0 Tesla with Quantitative Imaging to map intracortical myelin (proxied by longitudinal relaxation time T

Indexed as

Gyrus CinguliMagnetic Resonance ImagingMajor Depressive DisorderMyelin SheathPrefrontal CortexAdultCase-Control StudiesFemaleHumansIronMaleMiddle AgedIron

Identifiers

PMID38902245
PMCPMC11190139

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.