Evidence map›Paper›PMID 38907039›Full record

ReviewNature reviews. Urology2025

Renal mass biopsy - a practical and clinicopathologically relevant approach to diagnosis.

Hussein Mansour, My-Anh Tran-Dang, Miles Walkden, Ekaterini Boleti, Ravi Barod, Prasad Patki, Faiz Mumtaz, Maxine G B Tran, Axel Bex, Soha El Sheikh

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hussein MansourResearch Department of Pathology, UCL Cancer Institute, London, UK.
My-Anh Tran-DangSpecialist centre for kidney cancer, Royal Free London Hospital, London, UK.
Miles WalkdenSpecialist centre for kidney cancer, Royal Free London Hospital, London, UK.
Ekaterini BoletiSpecialist centre for kidney cancer, Royal Free London Hospital, London, UK.
Ravi BarodSpecialist centre for kidney cancer, Royal Free London Hospital, London, UK.
Prasad PatkiSpecialist centre for kidney cancer, Royal Free London Hospital, London, UK.
Faiz MumtazSpecialist centre for kidney cancer, Royal Free London Hospital, London, UK.
Maxine G B TranSpecialist centre for kidney cancer, Royal Free London Hospital, London, UK.
Axel BexSpecialist centre for kidney cancer, Royal Free London Hospital, London, UK.
Soha El SheikhResearch Department of Pathology, UCL Cancer Institute, London, UK. soha.sheikh@ucl.ac.uk.ORCID 0000-0003-4661-1563

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advancements in imaging modalities have increased the frequency of renal mass discovery. Imaging has typically been considered sufficient to guide management for a large proportion of these tumours, but renal mass biopsies (RMBs) have an increasing role in determining malignancy and can be a valuable tool for preventing unnecessary surgery in patients with benign tumours. A structured approach should be used to help to navigate the expanding repertoire of renal tumours, many of which are molecularly defined. In terms of tumour subtyping, the pathologist's strategy should focus on stratifying patients into clinically different prognostic groups according to our current knowledge of tumour behaviour, including benign, low-grade or indolent, intermediate malignant or highly aggressive. Crucial pathological features and morphological mimicry of tumours can alter the tumour's prognostic group. Thus, pathologists and urologists can use RMB to select patients with tumours at a reduced risk of progression, which can be safely managed with active surveillance within a tailored imaging schedule, versus tumours for which ablation or surgical intervention is indicated. RMB is also crucial in the oncological setting to distinguish between different high-grade tumours and guide tailored management strategies.

Indexed as

KidneyKidney NeoplasmsBiopsyHumans

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.