Evidence map›Paper›PMID 38907938›Full record

ArticleCell biochemistry and biophysics2024

Biologically Synthesized Gold Nanoparticles Mitigate Aluminum Chloride-Induced Nephrotoxicity via Downregulation of iNOX, LCN2 and IL-1β Genes.

Scholastica O Anadozie, Asueiza U Aduma, Olusola B Adewale

Abstract read
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In one paragraph

Article in Cell biochemistry and biophysics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Scholastica O AnadozieNanomedicine, Drug Metabolism and Toxicology Research Laboratory, Biochemistry Program, Department of Chemical Sciences, Afe Babalola University, P.M.B 5454, Ado-Ekiti, Nigeria. anadozieso@abuad.edu.ng.ORCID http://orcid.org/0000-0003-4118-4611
Asueiza U AdumaDepartment of Internal Medicine, Afe Babalola University Teaching Hospital, P.M.B 5454, Ado-Ekiti, Nigeria.
Olusola B AdewaleNanomedicine, Drug Metabolism and Toxicology Research Laboratory, Biochemistry Program, Department of Chemical Sciences, Afe Babalola University, P.M.B 5454, Ado-Ekiti, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Humans are constantly exposed to aluminum (Al), an environmental toxicant, and its accumulation in the glomerular could lead to acute kidney disease. Biologically synthesized gold nanoparticles (AuNPs) have been employed in the management of kidney disorders. This study assessed the modulatory effect of AuNPs mediated by Hibiscus sabdariffa (HS) on aluminum chloride (AlCl

Indexed as

Aluminum ChlorideDown-RegulationGoldInterleukin-1betaKidneyLipocalin-2Metal NanoparticlesAluminum CompoundsAnimalsArginaseChloridesGlutathioneHibiscusKidney DiseasesMaleMalondialdehydeAluminum ChlorideAluminum CompoundsArginaseChloridesGlutathioneGoldInterleukin-1betaLcn2 protein, ratLipocalin-2MalondialdehydeNitric Oxide Synthase Type IIPlant ExtractsSuperoxide DismutaseAluminum chlorideGold nanoparticlesHibiscus sabdariffaLipocalin 2NephrotoxicityOxidative biomarkers

Identifiers

PMID38907938

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.