ArticleDiabetes care2024
Consensus Guidance for Monitoring Individuals With Islet Autoantibody-Positive Pre-Stage 3 Type 1 Diabetes.
Erratum issuedAbstract readConsensus Statement
In one paragraph
Article in Diabetes care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 78 papers, 6 of them syntheses that pooled it.
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78citing papers in PubMed, 6 pooled it
–field-weighted citation impact
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
78 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Psychosocial implications, acceptability and ethics of screening for paediatric type 1 diabetes: a systematic review and mixed methods evidence synthesis.Diabetologia · 2026Pooled it
- Impact of screening programmes for type 1 diabetes in youth: A systematic review and meta-analysis.Diabetic medicine : a journal of the British Diabetic Association · 2026Pooled it
- Polish Recommendations for the Early Detection of Type 1 Diabetes in the Pediatric Population: A Position Statement of the Polish Society of Pediatric Endocrinology and Diabetology and the Pediatric Section of the Diabetes Poland 2026.Hormone research in paediatrics · 2026Guideline
- UK best practice recommendations for children and young people <18 years with pre-stage 3 type 1 diabetes, on behalf of the British Society for Paediatric Endocrinology and Diabetes (BSPED).Diabetic medicine : a journal of the British Diabetic Association · 2025Guideline
- Testing methods used to predict disease progression in children with early-stage type 1 diabetes: A systematic review and meta-analysis.Diabetic medicine : a journal of the British Diabetic Association · 2025Pooled it
- ISPAD Clinical Practice Consensus Guidelines 2024: Screening, Staging, and Strategies to Preserve Beta-Cell Function in Children and Adolescents with Type 1 Diabetes.Hormone research in paediatrics · 2024Guideline
- Effect of High-Dose Oral Insulin in Children With Stage 1 Type 1 Diabetes: The Fr1da Insulin Intervention Randomized Controlled Trial.Diabetes care · 2026Trial
- Article
- Impact of Autoimmune Hypothyroidism and Celiac Disease on Progression to Diabetes in Individuals Positive for GAD65 or IA-2 Autoantibodies.Diabetes, obesity & metabolism · 2026Article
- Improved prediction of symptomatic type 1 diabetes using a luciferase-based assay to measure (pro)insulin autoantibodies.Diabetic medicine : a journal of the British Diabetic Association · 2026Observational
- Screening of pre-type 1 diabetes in high-risk paediatric population: a pilot study in Latvia.European journal of pediatrics · 2026Observational
- The Evolving Landscape of Continuous Glucose Monitoring Metrics in Type 1 Diabetes: Narrative Literature Review.JMIR diabetes · 2026Review
- Consensus Recommendations for the Clinical Management of Wolfram syndrome Using a Delphi Method.medRxiv : the preprint server for health sciences · 2026Article
- Differences in Clinical Manifestations and Islet Autoantibodies by Age in Adult-Onset Type 1 Diabetes.Diabetes care · 2026Article
- Considerations for the clinical use of teplizumab in stage 2 Type 1 diabetes: A Consensus Statement from the British Society of Paediatric Endocrinology and Diabetes (BSPED) and the Association of British Clinical Diabetologists (ABCD).Diabetic medicine : a journal of the British Diabetic Association · 2026Article
- Islet Autoantibodies in Adult With Pituitary and Ovarian Autoimmunity: Implications for Type 1 Diabetes Screening.Diabetes, obesity & metabolism · 2026Article
- Tailoring interventions to close gaps in diabetes mellitus care.Nature reviews. Endocrinology · 2026Review
- The Risk of Disease Progression of Type 1 Diabetes in First-Degree Relatives of People With Type 1 Diabetes: Design and Rationale of a Prospective, Longitudinal Study in China.Diabetes, obesity & metabolism · 2026Article
- Frequency of islet autoantibody seropositivity among adults with newly diagnosed type 2 diabetes in the Kazakh population: A cross-sectional study.Journal of diabetes investigation · 2026Article
- Exploring the psychosocial implications of general population screening for paediatric type 1 diabetes in Europe: Protocol for a mixed-methods study.Diabetic medicine : a journal of the British Diabetic Association · 2026Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
66 authors.
Moshe PhillipInstitute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children's Medical Center of Israel, Petah Tikva, Israel.ORCID 0000-0002-6616-5612
Peter AchenbachInstitute of Diabetes Research, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany.ORCID 0000-0001-6720-2684
Ananta AddalaDivision of Endocrinology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.ORCID 0000-0002-0508-4309
Anastasia Albanese-O'NeillBreakthrough T1D, Gainesville, FL.ORCID 0000-0001-8219-6059
Tadej BattelinoFaculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.ORCID 0000-0002-0273-4732
Kirstine J BellCharles Perkins Centre and Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0001-5638-4048
Rachel E J BesserJDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre Human Genetics, Nuffield Department of Medicine Oxford National Institute for Health and Care Research Biomedical Research Centre, University of Oxford, Oxford, U.K.ORCID 0000-0002-4645-6324
Ezio BonifacioCenter for Regenerative Therapies Dresden, Faculty of Medicine, Technical University of Dresden, Dresden, Germany.ORCID 0000-0002-8704-4713
Helen M ColhounThe Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, U.K.ORCID 0000-0002-8345-3288
Jennifer J CouperRobinson Research Institute, The University of Adelaide, Adelaide, South Australia, Australia.ORCID 0000-0003-4448-8629
Maria E CraigCharles Perkins Centre and Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0001-6004-576X
Thomas DanneBreakthrough T1D, Lisbon.ORCID 0000-0003-0773-6961
Carine de BeaufortInternational Society for Pediatric and Adolescent Diabetes (ISPAD), Berlin, Germany.ORCID 0000-0003-4310-6799
Klemen DovcFaculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.ORCID 0000-0001-9201-2145
Kimberly A DriscollDepartment of Pediatrics, Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO.ORCID 0000-0002-3006-4633
Sanjoy DuttaBreakthrough T1D, New York, NY.ORCID 0000-0001-8117-1677
Osagie EbekozienT1D Exchange, Boston, MA.ORCID 0000-0002-8473-249X
Helena Elding LarssonDepartment of Clinical Sciences, Malmö, Lund University, Lund, Sweden.ORCID 0000-0003-3306-1742
Daniel J FeitenChildren's Diabetes Foundation, Aurora, CO.ORCID 0000-0005-9922-7305
Brigitte I FrohnertDepartment of Pediatrics, Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO.
Robert A GabbayAmerican Diabetes Association, Arlington, VA.ORCID 0000-0003-3541-1486
Mary P GallagherNYU Langone Medical Center, New York, NY.ORCID 0000-0002-5844-2309
Carla J GreenbaumCenter for Interventional Immunology and Diabetes Program, Benaroya Research Institute, Seattle, WA.ORCID 0000-0003-4451-9800
Kurt J GriffinSanford Research, Sioux Falls, SD.ORCID 0000-0003-2374-0733
William HagopianPacific Northwest Diabetes Research Institute, University of Washington, Seattle, WA.
Michael J HallerDepartment of Pediatrics, University of Florida Diabetes Institute, Gainesville, FL.ORCID 0000-0000-2803-1824
Christel HendrieckxSchool of Psychology, Deakin University, Geelong, Victoria, Australia.ORCID 0000-0002-0075-828X
Emile HendriksDepartment of Paediatrics, University of Cambridge and Cambridge University Hospitals NHS Foundation Trust, Cambridge, U.K.ORCID 0000-0002-0795-1832
Richard I G HoltHuman Development and Health, Faculty of Medicine, University of Southampton, Southampton, U.K.ORCID 0000-0001-8911-6744
Lucille HughesMount Sinai South Nassau, Oceanside, NY.
Heba M IsmailDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.ORCID 0000-0003-0102-0030
Laura M JacobsenDivision of Endocrinology, University of Florida College of Medicine, Gainesville, FL.ORCID 0000-0002-5144-7836
Suzanne B JohnsonDepartment of Behavioral Sciences and Social Medicine, Florida State University College of Medicine, Tallahassee, FL.ORCID 0000-0001-5721-7524
Leslie E KolbAssociation of Diabetes Care & Education Specialists, Chicago, IL.ORCID 0000-0003-2803-6788
Olga KordonouriBreakthrough T1D, Lisbon.ORCID 0000-0001-9563-3537
Karin LangeMedical Psychology, Hannover Medical School, Hannover, Germany.ORCID 0000-0002-3636-2025
Robert W LashEndocrine Society, Washington, DC.ORCID 0000-0003-2457-4888
Åke LernmarkDepartment of Clinical Sciences, Malmö, Lund University, Lund, Sweden.ORCID 0000-0003-1735-0499
Ingrid LibmanDivision of Pediatric Endocrinology and Diabetes, University of Pittsburgh, University of Pittsburgh Medical Center Children's Hospital of Pittsburgh, PA.ORCID 0000-0002-0255-4555
Markus LundgrenDepartment of Clinical Sciences, Malmö, Lund University, Lund, Sweden.ORCID 0000-0001-6394-7689
David M MaahsDivision of Endocrinology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.ORCID 0000-0002-4602-7909
M Loredana MarcovecchioDepartment of Pediatrics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, U.K.ORCID 0000-0002-4415-316X
Chantal MathieuDepartment of Endocrinology, UZ Gasthuisberg, KU Leuven, Leuven, Belgium.ORCID 0000-0002-4055-5233
Kellee M MillerT1D Exchange, Boston, MA.
Holly K O'DonnellDepartment of Pediatrics, Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO.ORCID 0000-0002-7774-7220
Tal OronInstitute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children's Medical Center of Israel, Petah Tikva, Israel.ORCID 0000-0001-9485-2738
Shivajirao P PatilDepartment of Family Medicine, Brody School of Medicine, East Carolina University, Greenville, NC.ORCID 0000-0001-9781-4809
Rodica Pop-BusuiDepartment of Internal Medicine, Division of Metabolism, Endocrinology and Diabetes, University of Michigan, Ann Arbor, MI.ORCID 0000-0002-2042-1350
Marian J RewersDepartment of Pediatrics, Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO.ORCID 0000-0003-3829-9207
Stephen S RichCenter for Public Health Genomics, University of Virginia, Charlottesville, VA.ORCID 0000-0003-3872-7793
Desmond A SchatzDepartment of Pediatrics, University of Florida, Gainesville, FL.ORCID 0000-0002-1044-5762
Rifka Schulman-RosenbaumDivision of Endocrinology, Long Island Jewish Medical Center, Northwell Health, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, NY.ORCID 0000-0003-4604-0879
Kimber M SimmonsDepartment of Pediatrics, Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO.ORCID 0000-0003-0560-5773
Emily K SimsDivision of Pediatric Endocrinology and Diabetology, Herman B Wells Center for Pediatric Research, Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.ORCID 0000-0002-4393-954X
Jay S SkylerDiabetes Research Institute, University of Miami Miller School of Medicine, Miami, FL.ORCID 0000-0003-1136-8110
Laura B SmithCincinnati Children's Hospital Medical Center, Cincinnati, OH.ORCID 0000-0002-3722-7490
Cate SpeakeCenter for Interventional Immunology and Diabetes Program, Benaroya Research Institute, Seattle, WA.ORCID 0000-0003-1480-4272
Andrea K SteckDepartment of Pediatrics, Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO.ORCID 0000-0002-5931-9484
Nicholas P B ThomasNational Institute of Health and Care Research Clinical Research Network Thames Valley and South Midlands, Oxford, U.K.ORCID 0000-0003-0460-6870
Ksenia N TonyushkinaDivision of Endocrinology and Diabetes, Baystate Children's Hospital and University of Massachusetts Chan Medical School-Baystate, Springfield, MA.ORCID 0000-0002-6415-8005
Riitta VeijolaResearch Unit of Clinical Medicine, Department of Pediatrics, Medical Research Center, Oulu University Hospital and University of Oulu, Oulu, Finland.ORCID 0000-0002-6557-270X
John M WentworthThe Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.ORCID 0000-0002-5197-3529
Diane K WherrettDepartment of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0003-0629-5316
Jamie R WoodDepartment of Pediatric Endocrinology, Rainbow Babies and Children's Hospital, University Hospitals Cleveland Medical Center, Cleveland, OH.
Anette-Gabriele ZieglerInstitute of Diabetes Research, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany.ORCID 0000-0002-6290-5548
Linda A DiMeglioMount Sinai South Nassau, Oceanside, NY.ORCID 0000-0002-8033-6078
Funding
NIDDK Diabetic Foot Consortium Clinical Research UnitU01DK119083 · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2025 to 2025
$727kNIDDK NIH HHS U01 DK119083
Abstract
Given the proven benefits of screening to reduce diabetic ketoacidosis (DKA) likelihood at the time of stage 3 type 1 diabetes diagnosis, and emerging availability of therapy to delay disease progression, type 1 diabetes screening programs are being increasingly emphasized. Once broadly implemented, screening initiatives will identify significant numbers of islet autoantibody-positive (IAb+) children and adults who are at risk for (confirmed single IAb+) or living with (multiple IAb+) early-stage (stage 1 and stage 2) type 1 diabetes. These individuals will need monitoring for disease progression; much of this care will happen in nonspecialized settings. To inform this monitoring, JDRF, in conjunction with international experts and societies, developed consensus guidance. Broad advice from this guidance includes the following: 1) partnerships should be fostered between endocrinologists and primary care providers to care for people who are IAb+; 2) when people who are IAb+ are initially identified, there is a need for confirmation using a second sample; 3) single IAb+ individuals are at lower risk of progression than multiple IAb+ individuals; 4) individuals with early-stage type 1 diabetes should have periodic medical monitoring, including regular assessments of glucose levels, regular education about symptoms of diabetes and DKA, and psychosocial support; 5) interested people with stage 2 type 1 diabetes should be offered trial participation or approved therapies; and 6) all health professionals involved in monitoring and care of individuals with type 1 diabetes have a responsibility to provide education. The guidance also emphasizes significant unmet needs for further research on early-stage type 1 diabetes to increase the rigor of future recommendations and inform clinical care.
Indexed as
AutoantibodiesDiabetes Mellitus, Type 1HumansIslets of LangerhansAutoantibodies
Identifiers
What Socratic holds
Textmetadata
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.