Evidence map›Paper›PMID 38919852›Full record

ArticleNature cardiovascular research2023

Nuclear Smooth Muscle α-actin Participates in Vascular Smooth Muscle Cell Differentiation.

Callie S Kwartler, Albert J Pedroza, Anita Kaw, Pujun Guan, Shuangtao Ma, Xue-Yan Duan, Caroline Kernell, Charis Wang, Jose Emiliano Esparza Pinelo, Mikayla S Borthwick Bowen and 6 more

Abstract read
In one paragraph

Article in Nature cardiovascular research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Recent advances in nuclear actin research.Nucleus (Austin, Tex.) · 2025
    Review
  9. Article
  10. Dysregulated smooth muscle cell proliferation and gene expression underlieAmerican journal of physiology. Heart and circulatory physiology · 2025
    Article
  11. Article
  12. Article
  13. Veterinary world · 2025
    Review
  14. Article
  15. Article
  16. Immature Acta2Nature communications · 2025
    Article
  17. Article
  18. Review
  19. Use of iPSC-Derived Smooth Muscle Cells to Model Physiology and Pathology.Arteriosclerosis, thrombosis, and vascular biology · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Callie S KwartlerDivision of Medical Genetics, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.
Albert J PedrozaDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA 94305.
Anita KawDivision of Medical Genetics, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.
Pujun GuanDivision of Medical Genetics, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.
Shuangtao MaDivision of Medical Genetics, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.
Xue-Yan DuanDivision of Medical Genetics, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.
Caroline KernellDivision of Medical Genetics, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.
Charis WangDivision of Medical Genetics, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.
Jose Emiliano Esparza PineloDivision of Medical Genetics, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.
Mikayla S Borthwick BowenDivision of Medical Genetics, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.
Jiyuan ChenDivision of Medical Genetics, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.
Yuan ZhongDepartment of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Smithville, TX 78957.
Sanjay SinhaWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.
Xuetong ShenInstitute of Cancer Research, Shenzhen Bay Laboratory, Shenzhen, China.
Michael P FischbeinDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA 94305.
Dianna M MilewiczDivision of Medical Genetics, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.

Funding

Convalescent Plasma to Limit Coronavirus Associated ComplicationsUL1TR003167 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KARP, DANIEL D, MCPHERSON, DAVID D · 2019 to 2023
$45.3M
NRSA Training CoreTL1TR003169 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI CHANDRA, JOYA, FROST, JEFFREY A. · 2019 to 2023
$3.7M
Marfan Aortic Embryologic Origin Influences Aneurysm FormationR01HL157949 · NHLBI · STANFORD UNIVERSITY · PI FISCHBEIN, MICHAEL PETER · 2022 to 2025
$2.6M
Novel genetic Insight into the molecular pathogenesis of atherosclerosisR01HL146583 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MILEWICZ, DIANNA M · 2019 to 2022
$2.6M
Developmental basis for vascular smooth muscle cell dysfunction in Marfan syndrome aortic aneurysmF32HL154681 · NHLBI · STANFORD UNIVERSITY · PI PEDROZA, ALBERT J. · 2020 to 2021
$137k
NCATS NIH HHS TL1 TR003169NCATS NIH HHS UL1 TR003167NHLBI NIH HHS F32 HL154681NHLBI NIH HHS R01 HL146583NHLBI NIH HHS R01 HL157949
6 · The paper itself

Abstract

Missense variants throughout

Identifiers

PMID38919852
PMCPMC11198982

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.