Evidence map›Paper›PMID 38919940›Full record

ArticleFrontiers in medicine2024

Post-COVID-19 condition: a sex-based analysis of clinical and laboratory trends.

Carlos Delfino, M Cecilia Poli, Cecilia Vial, Pablo A Vial, Gonzalo Martínez, Amy Riviotta, Catalina Arbat, Nicole Mac-Guire, Josefina Hoppe, Cristóbal Carvajal and 1 more

Abstract read
In one paragraph

Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Carlos DelfinoCentro de Estudios Clínicos, Instituto de Ciencias e Innovación en Medicina (ICIM), Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago, Chile.
M Cecilia PoliFacultad de Medicina Clínica Alemana de Santiago, Universidad del Desarrollo, Santiago, Chile.
Cecilia VialFacultad de Medicina Clínica Alemana de Santiago, Universidad del Desarrollo, Santiago, Chile.
Pablo A VialFacultad de Medicina Clínica Alemana de Santiago, Universidad del Desarrollo, Santiago, Chile.
Gonzalo MartínezDepartamento de Enfermedades Cardiovasculares, Pontificia Universidad Católica de Chile, Santiago, Chile.
Amy RiviottaCentro de Estudios Clínicos, Instituto de Ciencias e Innovación en Medicina (ICIM), Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago, Chile.
Catalina ArbatFacultad de Medicina Clínica Alemana de Santiago, Universidad del Desarrollo, Santiago, Chile.
Nicole Mac-GuireFacultad de Medicina Clínica Alemana de Santiago, Universidad del Desarrollo, Santiago, Chile.
Josefina HoppeFacultad de Medicina Clínica Alemana de Santiago, Universidad del Desarrollo, Santiago, Chile.
Cristóbal CarvajalCentro de Informática Biomédica, Instituto de Ciencias e Innovación en Medicina (ICIM), Facultad de Medicina Clínica Alemana-Universidad del Desarrollo, Santiago, Chile.
Paula Muñoz VenturelliCentro de Estudios Clínicos, Instituto de Ciencias e Innovación en Medicina (ICIM), Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aim: Post-COVID-19 condition (PCC) encompasses long-lasting symptoms in individuals with COVID-19 and is estimated to affect between 31-67% of patients, with women being more commonly affected. No definitive biomarkers have emerged in the acute stage that can help predict the onset of PCC, therefore we aimed at describing sex-disaggregated data of PCC patients from a local cohort and explore potential acute predictors of PCC and neurologic PCC. Methods: A local cohort of consecutive patients admitted with COVID-19 diagnosis between June 2020 and July 2021 were registered, and clinical and laboratory data were recorded. Only those <65 years, discharged alive and followed up at 6 and 12 months after admission were considered in these analyses. Multivariable logistic regression analysis was performed to explore variables associated with PCC (STATA v 18.0). Results: From 130 patients in the cohort, 104 were contacted: 30% were women, median age of 42 years. At 6 months, 71 (68%) reported PCC symptoms. Women exhibited a higher prevalence of any PCC symptom (87 vs. 60%, Conclusion: Our findings highlight the lasting impact of COVID-19, particularly in young women, emphasising the need for tailored post-COVID care. The lower ferritin levels in women are an intriguing observation, warranting further research. The study argues for comprehensive strategies that address sex-specific challenges in recovery from COVID-19.

Indexed as

COVID-19long COVIDneurologic long-COVID-19post COVID-19 conditionsex-disaggregated

Identifiers

PMID38919940
PMCPMC11198115

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.