Evidence map›Paper›PMID 38924786›Full record

ArticleJMIR mHealth and uHealth2024

Detection of Mild Cognitive Impairment Through Hand Motor Function Under Digital Cognitive Test: Mixed Methods Study.

Aoyu Li, Jingwen Li, Jiali Chai, Wei Wu, Suamn Chaudhary, Juanjuan Zhao, Yan Qiang

Abstract read
In one paragraph

Article in JMIR mHealth and uHealth, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aoyu LiSchool of Software, Taiyuan University of Technology, Jinzhong, China.ORCID 0000-0001-5249-9964
Jingwen LiSchool of Computer Science, Xijing University, Xian, China.ORCID 0009-0001-7991-6622
Jiali ChaiCollege of Computer Science and Technology (College of Data Science), Taiyuan University of Technology, Jinzhong, China.ORCID 0009-0003-1607-5429
Wei WuShanxi Provincial People's Hospital, Taiyuan, China.ORCID 0000-0002-1336-1222
Suamn ChaudharyCollege of Computer Science and Technology (College of Data Science), Taiyuan University of Technology, Jinzhong, China.ORCID 0009-0005-6996-0813
Juanjuan ZhaoCollege of Computer Science and Technology (College of Data Science), Taiyuan University of Technology, Jinzhong, China.ORCID 0009-0001-4684-8897
Yan QiangCollege of Computer Science and Technology (College of Data Science), Taiyuan University of Technology, Jinzhong, China.ORCID 0000-0001-6231-3721

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly detection of cognitive impairment or dementia is essential to reduce the incidence of severe neurodegenerative diseases. However, currently available diagnostic tools for detecting mild cognitive impairment (MCI) or dementia are time-consuming, expensive, or not widely accessible. Hence, exploring more effective methods to assist clinicians in detecting MCI is necessary.

objectiveIn this study, we aimed to explore the feasibility and efficiency of assessing MCI through movement kinetics under tablet-based "drawing and dragging" tasks.

methodsWe iteratively designed "drawing and dragging" tasks by conducting symposiums, programming, and interviews with stakeholders (neurologists, nurses, engineers, patients with MCI, healthy older adults, and caregivers). Subsequently, stroke patterns and movement kinetics were evaluated in healthy control and MCI groups by comparing 5 categories of features related to hand motor function (ie, time, stroke, frequency, score, and sequence). Finally, user experience with the overall cognitive screening system was investigated using structured questionnaires and unstructured interviews, and their suggestions were recorded.

resultsThe "drawing and dragging" tasks can detect MCI effectively, with an average accuracy of 85% (SD 2%). Using statistical comparison of movement kinetics, we discovered that the time- and score-based features are the most effective among all the features. Specifically, compared with the healthy control group, the MCI group showed a significant increase in the time they took for the hand to switch from one stroke to the next, with longer drawing times, slow dragging, and lower scores. In addition, patients with MCI had poorer decision-making strategies and visual perception of drawing sequence features, as evidenced by adding auxiliary information and losing more local details in the drawing. Feedback from user experience indicates that our system is user-friendly and facilitates screening for deficits in self-perception.

conclusionsThe tablet-based MCI detection system quantitatively assesses hand motor function in older adults and further elucidates the cognitive and behavioral decline phenomenon in patients with MCI. This innovative approach serves to identify and measure digital biomarkers associated with MCI or Alzheimer dementia, enabling the monitoring of changes in patients' executive function and visual perceptual abilities as the disease advances.

Indexed as

Cognitive DysfunctionAgedAged, 80 and overFemaleHandHumansMaleMiddle AgedNeuropsychological TestsQualitative ResearchSurveys and Questionnairesdigital cognitive testdual taskmild cognitive impairmentmobile phonemovement kinetics

Identifiers

PMID38924786
PMCPMC11237787

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.