Evidence map›Paper›PMID 38926462›Full record

ArticleInternational journal of obesity (2005)2024

Metabolic obesity phenotypes and all-cause mortality among the Chinese oldest-old population: a prospective cohort study.

Wei-Qi Song, Wen-Fang Zhong, Jian Gao, Zhi-Hao Li, Jiao-Jiao Ren, Dong Shen, Xiao-Meng Wang, Qiao-Qiao Shen, Fang-Fei You, Qi Fu and 5 more

Abstract read
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In one paragraph

Article in International journal of obesity (2005), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Wei-Qi Song *Department of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
Wen-Fang Zhong *Department of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
Jian GaoDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
Zhi-Hao LiDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
Jiao-Jiao RenDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
Dong ShenDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
Xiao-Meng WangDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
Qiao-Qiao ShenDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
Fang-Fei YouDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
Qi FuDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
Chuan LiDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
Huan ChenDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
Yue-Bin LvNational Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Xiao-Ming ShiNational Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China. shixm@chinacdc.cn.ORCID 0000-0002-7071-571X
Chen MaoDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China. maochen9@smu.edu.cn.ORCID 0000-0002-6537-6215

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe obesity paradox has been reported among older adults. However, whether the favorable effect of obesity is dependent on metabolic status remains largely unknown. We aimed to explore the association of metabolic obesity phenotypes and their changes with all-cause mortality among the Chinese oldest-old population.

methodsThis prospective cohort study included 1207 Chinese oldest old (mean age: 91.8 years). Metabolic obesity phenotypes were determined by central obesity and metabolic status, and participants were classified into metabolically healthy obesity (MHO), metabolically unhealthy obesity (MUO), metabolically healthy non-obesity (MHN), and metabolically unhealthy non-obesity (MUN). The hazard ratios (HRs) and 95% confidence intervals (95% CIs) were estimated by Cox regression models.

resultsDuring 5.3 years of follow-up, 640 deaths were documented. Compared with non-obesity, obesity was associated with a decreased mortality risk among participants with metabolically healthy (HR, 0.75; 95% CI, 0.63-0.91) while this association was insignificant among metabolically unhealthy. Compared to MHO, MHN (HR, 1.27; 95% CI, 1.06-1.53) and MUN (HR, 1.49; 95% CI, 1.10-2.02) were significantly associated with an increased mortality risk. Compared to those with stable MHO, those transited from MHO to MUO demonstrated a higher mortality risk (HR, 1.81; 95% CI, 1.06-3.11).

conclusionsMHO predicts better survival among the Chinese oldest-old population. These findings suggest that ensuring optimal management of metabolic health is beneficial and taking caution in weight loss based on the individual body weight for the metabolically healthy oldest-old adults.

Indexed as

ObesityPhenotypeAged, 80 and overCause of DeathChinaEast Asian PeopleFemaleHumansMaleMetabolic SyndromeMortalityProspective StudiesRisk Factors

Identifiers

PMID38926462

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.