Evidence map›Paper›PMID 38926483›Full record

ArticleScientific reports2024

NMR-based metabolomics identification of potential serum biomarkers of disease progression in patients with multiple sclerosis.

Mohammad Alwahsh, Refat M Nimer, Lina A Dahabiyeh, Lama Hamadneh, Aya Hasan, Rahaf Alejel, Roland Hergenröder

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. PlasmaNeurology(R) neuroimmunology & neuroinflammation · 2025
    Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohammad Alwahsh *Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, 17138, Jordan. m.alwahsh@zuj.edu.jo.
Refat M Nimer *Department of Medical Laboratory Sciences, Jordan University of Science and Technology, Irbid, 22110, Jordan.
Lina A DahabiyehDepartment of Pharmaceutical Sciences, School of Pharmacy, The University of Jordan, Amman, 11942, Jordan.
Lama HamadnehDepartment of Badic Medical Sciences, Faculty of Medicine, Al-Balqa Applied University, Al-Salt, Jordan.
Aya HasanFaculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, 17138, Jordan.
Rahaf AlejelFaculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, 17138, Jordan.
Roland HergenröderLeibniz-Institut Für Analytische Wissenschaften-ISAS-E.V., 44139, Dortmund, Germany.

Funding

Al-Zaytoonah University of Jordan (2022- 2023/11/39)Ministerium für Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen, and the Bundesministerium für Bildung und Forschung (01KU1216I)
6 · The paper itself

Abstract

Multiple sclerosis (MS) is a chronic and progressive neurological disorder, characterized by neuroinflammation and demyelination within the central nervous system (CNS). The etiology and the pathogenesis of MS are still unknown. Till now, no satisfactory treatments, diagnostic and prognostic biomarkers are available for MS. Therefore, we aimed to investigate metabolic alterations in patients with MS compared to controls and across MS subtypes. Metabolic profiles of serum samples from patients with MS (n = 90) and healthy control (n = 30) were determined by Nuclear Magnetic Resonance (

Indexed as

BiomarkersDisease ProgressionMagnetic Resonance SpectroscopyMetabolomicsMultiple SclerosisAdultCase-Control StudiesFemaleHumansMaleMetabolomeMiddle AgedBiomarkersBiomarkerMetabolomicMultiple sclerosisNuclear magnetic resonance spectroscopyRelapsing remitting

Identifiers

PMID38926483
PMCPMC11208524

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.