Evidence map›Paper›PMID 38927267›Full record

ReviewBiology2024

Exosomes in the Diagnosis of Neuropsychiatric Diseases: A Review.

Song Wu, Xinmiao Shang, Meng Guo, Lei Su, Jun Wang

Abstract readReview
In one paragraph

Review in Biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Song WuAutism & Depression Diagnosis and Intervention Institute, Hubei University of Technology, Wuhan 430068, China.
Xinmiao ShangAutism & Depression Diagnosis and Intervention Institute, Hubei University of Technology, Wuhan 430068, China.
Meng GuoAutism & Depression Diagnosis and Intervention Institute, Hubei University of Technology, Wuhan 430068, China.
Lei SuShenzhen Key Laboratory of Nano-Biosensing Technology, Marshall Laboratory of Biomedical Engineering, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518060, China.ORCID 0000-0001-5342-1552
Jun WangAutism & Depression Diagnosis and Intervention Institute, Hubei University of Technology, Wuhan 430068, China.

Funding

Department of Science & Technology of Hubei Province Grant GJHZ2023000081Hubei Provincial Department of Education Grant T2020009Ministry of Science and Technology of the People's Republic of China Grant G2022027010LNational Natural Science Foundation of China International Collaborative Grant 82061138005
6 · The paper itself

Abstract

Exosomes are 30-150 nm small extracellular vesicles (sEVs) which are highly stable and encapsulated by a phospholipid bilayer. Exosomes contain proteins, lipids, RNAs (mRNAs, microRNAs/miRNAs, long non-coding RNAs/lncRNAs), and DNA of their parent cell. In pathological conditions, the composition of exosomes is altered, making exosomes a potential source of biomarkers for disease diagnosis. Exosomes can cross the blood-brain barrier (BBB), which is an advantage for using exosomes in the diagnosis of central nervous system (CNS) diseases. Neuropsychiatric diseases belong to the CNS diseases, and many potential diagnostic markers have been identified for neuropsychiatric diseases. Here, we review the potential diagnostic markers of exosomes in neuropsychiatric diseases and discuss the potential application of exosomal biomarkers in the early and accurate diagnosis of these diseases. Additionally, we outline the limitations and future directions of exosomes in the diagnosis of neuropsychiatric diseases.

Indexed as

central nervous system diseasediagnosisexosomeneuropsychiatric disease

Identifiers

PMID38927267
PMCPMC11200774

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.