Evidence map›Paper›PMID 38928411›Full record

ArticleInternational journal of molecular sciences2024

Comprehensive Analysis of Gut Microbiota Composition and Functional Metabolism in Children with Autism Spectrum Disorder and Neurotypical Children: Implications for Sex-Based Differences and Metabolic Dysregulation.

Amapola De Sales-Millán, Paulina Reyes-Ferreira, José Félix Aguirre-Garrido, Ismene Corral-Guillé, Rehotbevely Barrientos-Ríos, José Antonio Velázquez-Aragón

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amapola De Sales-MillánDoctorado en Ciencias Biológicas y de la Salud, Universidad Autónoma Metropolitana, Ciudad de México 09340, Mexico.ORCID 0000-0002-2527-8055
Paulina Reyes-FerreiraDepartamento de Salud Mental, Instituto Nacional de Pediatría, Ciudad de México 04530, Mexico.
José Félix Aguirre-GarridoDepartamento de Ciencias Ambientales, Universidad Autónoma Metropolitana-Lerma, Lerma 52006, Estado de Mexico, Mexico.ORCID 0000-0002-4017-3753
Ismene Corral-GuilléCentro de Investigación del Neurodesarrollo, Instituto Nacional de Pediatría, Ciudad de México 04530, Mexico.
Rehotbevely Barrientos-RíosLaboratorio de Citogenética, Instituto Nacional de Pediatría, Ciudad de México 04530, Mexico.
José Antonio Velázquez-AragónLaboratorio de Oncología Experimental, Instituto Nacional de Pediatría, Ciudad de México 04530, Mexico.ORCID 0000-0002-3617-8148

Funding

Instituto Nacional de Pediatria Recursos Fiscales 2022, 2023, 2024 Programa E022 Investigación y Desarrollo Tecnológico en Salud
6 · The paper itself

Abstract

This study aimed to investigate the gut microbiota composition in children with autism spectrum disorder (ASD) compared to neurotypical (NT) children, with a focus on identifying potential differences in gut bacteria between these groups. The microbiota was analyzed through the massive sequencing of region V3-V4 of the 16S RNA gene, utilizing DNA extracted from stool samples of participants. Our findings revealed no significant differences in the dominant bacterial phyla (Firmicutes, Bacteroidota, Actinobacteria, Proteobacteria, Verrucomicrobiota) between the ASD and NT groups. However, at the genus level, notable disparities were observed in the abundance of

Indexed as

Autism Spectrum DisorderGastrointestinal MicrobiomeBacteriaChildChild, PreschoolFecesFemaleHumansMaleMetabolic Networks and PathwaysRNA, Ribosomal, 16SSex CharacteristicsSex FactorsRNA, Ribosomal, 16Sautism spectrum disorderdysbiosisgut microbiotagut microbiota sex differencesmetabolic dysregulation

Identifiers

PMID38928411
PMCPMC11203636

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.