Evidence mapPaperPMID 38929190Full record

ReviewAntioxidants (Basel, Switzerland)2024

Potentials of Natural Antioxidants in Reducing Inflammation and Oxidative Stress in Chronic Kidney Disease.

On Ying Angela Lee, Alex Ngai Nick Wong, Ching Yan Ho, Ka Wai Tse, Angela Zaneta Chan, George Pak-Heng Leung, Yiu Wa Kwan, Martin Ho Yin Yeung

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
  7. Review
  8. International journal of molecular sciences · 2025
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Antioxidants (Basel, Switzerland) · 2025
    Article
  16. Review
  17. Review
  18. Article
  19. Frontiers in pharmacology · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

On Ying Angela LeeDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, China.
Alex Ngai Nick WongDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, China.ORCID 0000-0003-2789-350X
Ching Yan HoDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, China.
Ka Wai TseDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, China.
Angela Zaneta ChanDepartment of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, China.
George Pak-Heng LeungDepartment of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0003-3529-9367
Yiu Wa KwanThe School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Martin Ho Yin YeungDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, China.ORCID 0000-0001-8063-2929

Funding

This study was supported by Departmental Start-up Fund for M.H.Y.Y. from The Hong Kong Polytechnic University. BD2B
6 · The paper itself

Abstract

Chronic kidney disease (CKD) presents a substantial global public health challenge, with high morbidity and mortality. CKD patients often experience dyslipidaemia and poor glycaemic control, further exacerbating inflammation and oxidative stress in the kidney. If left untreated, these metabolic symptoms can progress to end-stage renal disease, necessitating long-term dialysis or kidney transplantation. Alleviating inflammation responses has become the standard approach in CKD management. Medications such as statins, metformin, and GLP-1 agonists, initially developed for treating metabolic dysregulation, demonstrate promising renal therapeutic benefits. The rising popularity of herbal remedies and supplements, perceived as natural antioxidants, has spurred investigations into their potential efficacy. Notably, lactoferrin,

Indexed as

antioxidantschronic kidney diseaseinflammationoxidative stressrenal preservation

Identifiers

PMID38929190
PMCPMC11201162

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.