ArticleChildren (Basel, Switzerland)2024
Clinical Characteristics of Offspring Born to Parents with Type 2 Diabetes Diagnosed in Youth: Observations from TODAY.
Jeanie B Tryggestad, Megan M Kelsey, Kimberly L Drews, Shirley Zhou, Nancy Chang, Elia Escaname, Samuel S Gidding, Elvira Isganaitis, Siripoom McKay, Rachana Shah and 2 more
Abstract read
In one paragraphArticle in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Jeanie B TryggestadDepartment of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73117, USA.ORCID 0000-0002-5050-0850 Megan M KelseyDepartment of Pediatric Endocrinology, University of Colorado Anschutz Medical Campus, Children's Hospital Colorado, Aurora, CO 80045, USA.
Shirley ZhouBiostatistics Center, George Washington University, Rockville, MD 20852, USA.
Nancy ChangChildren's Hospital of Los Angeles, Los Angeles, CA 90027, USA.
Elia EscanameDepartment of Pediatrics, UT Health San Antonio, San Antonio, TX 78229, USA.
Samuel S GiddingGeisinger Health, Danville, PA 17822, USA.
Elvira IsganaitisDepartment of Pediatrics, Joslin Diabetes Center, Harvard Medical School, Boston, MA 02215, USA.
Siripoom McKayDepartment of Pediatric Diabetes and Endocrinology, Baylor College of Medicine, Houston, TX 77030, USA.
Rachana ShahDivision of Endocrinology and Diabetes, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.ORCID 0000-0001-7866-557X Michelle Van NameDepartment of Endocrinology, Yale School of Medicine, New Haven, CT 06510, USA.
TODAY Study Group
Funding
Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) StudyU01DK061230 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI BRAFFETT, BARBARA HALINA, ZEITLER, PHILIP S. · 2001 to 2019
$231.8MYale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9MSPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI JEAN E. SCHAFFER · 1986 to 2026
$50.5MPILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Paul S. Maclean · 1995 to 2026
$32.6MManagement of Pediatric Type 2 Diabetes MellitusU01DK061239 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI KATZ, LORRAINE E LEVITT · 2001 to 2008
$6.9MMulti-Center Study of the Treatment of T2DM in YouthU01DK061212 · NIDDK · YALE UNIVERSITY · PI CAPRIO, SONIA · 2001 to 2008
$5.3MTreatment Alternatives in Pediatric Type 2 DiabetesU01DK061242 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI ZEITLER, PHILIP S. · 2001 to 2008
$5.1MType 2 Diabetes in Youth: Beta Cell PreservationU01DK061254 · NIDDK · CHILDREN'S HOSP PITTSBURGH/UPMC HLTH SYS · PI ARSLANIAN, SILVA A · 2001 to 2007
$4.1MNCATS NIH HHS UL1 TR001863NIDDK NIH HHS P30 DK036836NIDDK NIH HHS U01 DK061230NIDDK NIH HHS U01-DK61212NIDDK NIH HHS U01-DK61230NIDDK NIH HHS U01-DK61239NIDDK NIH HHS U01-DK61242NIDDK NIH HHS U01-DK61254
6 · The paper itselfAbstract
Diabetes exposure during pregnancy affects health outcomes in offspring; however, little is known about in utero exposure to preexisting parental youth-onset type 2 diabetes. Offspring born to participants during the Treatment Options for Type 2 Diabetes in Adolescent and Youth (TODAY) study were administered a questionnaire at the end of the study. Of 457 participants, 37% of women and 18% of men reported 228 offspring, 80% from female participants. TODAY mothers had lower household income (<$25,000) compared to TODAY fathers (69.4% vs. 37.9%,
Indexed as
diabetesmedication useobesityperinatal complicationsrecidivism
Identifiers
PMID38929210
PMCPMC11201816
What Socratic holds
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