Safety and Tolerability of Continuous Inhaled Iloprost Therapy for Severe Pulmonary Hypertension in Neonates and Infants.

Amit V Krishnan, Victoria Freniere, Rakesh Sahni, Diana P Vargas Chaves, Sankaran S Krishnan, Dimitrios Savva, Usha S Krishnan

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In one paragraph

Article in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Pediatric Use of Inhaled Iloprost.Pulmonary circulation · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amit V KrishnanDepartment of Pediatrics (Cardiology), Columbia University Irving Medical Center, New York, NY 10932, USA.

Victoria FreniereDepartment of Pharmacy, New York-Presbyterian Hospital, New York, NY 10065, USA.ORCID 0000-0001-5385-8279

Rakesh SahniDepartment of Pediatrics (Neonatology), Columbia University Irving Medical Center, New York, NY 10032, USA.

Diana P Vargas ChavesDepartment of Pediatrics (Neonatology), Columbia University Irving Medical Center, New York, NY 10032, USA.

Sankaran S KrishnanDepartment of Pediatrics, New York Medical College, Valhalla, NY 10595, USA.

Dimitrios SavvaDepartment of Pharmacy, New York-Presbyterian Hospital, New York, NY 10065, USA.

Usha S KrishnanDepartment of Pediatrics (Cardiology), Columbia University Irving Medical Center, New York, NY 10932, USA.ORCID 0000-0002-5733-6096

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is a single-center retrospective study to assess the safety and tolerability of continuous inhaled iloprost use as rescue therapy for refractory pulmonary hypertension (PH) in critically ill neonates and infants. A retrospective chart review was performed on 58 infants and data were collected at baseline, 1, 6, 12, 24, 48 and 72 h of iloprost initiation. Primary outcomes were change in heart rate (HR), fraction of inspired oxygen (FiO

Indexed as

continuous iloprostinfantneonateoutcomepulmonary hypertension

Identifiers

PMID38929282

DOI10.3390/children11060703

PMCPMC11201391

What Socratic holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.