Evidence map›Paper›PMID 38930959›Full record

ArticleMolecules (Basel, Switzerland)2024

Synthesis of Novel Nitro-Halogenated Aryl-Himachalene Sesquiterpenes from Atlas Cedar Oil Components: Characterization, DFT Studies, and Molecular Docking Analysis against Various Isolated Smooth Muscles.

Youssef Edder, Issam Louchachha, Abdelmajid Faris, Mohamed Maatallah, Khalil Azzaoui, Mohammed Zerrouk, Mohamed Saadi, Lahcen El Ammari, Moha Berraho, Mohammed Merzouki and 7 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Youssef EdderLaboratory of Molecular Chemistry, Faculty of Sciences Semlalia, Cadi Ayyad University, BP 2390, Marrakech 40001, Morocco.
Issam LouchachhaLaboratory of Molecular Chemistry, Faculty of Sciences Semlalia, Cadi Ayyad University, BP 2390, Marrakech 40001, Morocco.
Abdelmajid FarisLaboratory of Molecular Chemistry, Faculty of Sciences Semlalia, Cadi Ayyad University, BP 2390, Marrakech 40001, Morocco.
Mohamed MaatallahLaboratory of Molecular Chemistry, Faculty of Sciences Semlalia, Cadi Ayyad University, BP 2390, Marrakech 40001, Morocco.ORCID 0000-0001-7921-8587
Khalil AzzaouiEngineering Laboratory of Organometallic, Molecular Materials, and Environment, Faculty of Sciences, University Sidi Mohamed Ben Abdellah, Fes 30000, Morocco.ORCID 0000-0003-0202-0112
Mohammed ZerroukEngineering Laboratory of Organometallic, Molecular Materials, and Environment, Faculty of Sciences, University Sidi Mohamed Ben Abdellah, Fes 30000, Morocco.ORCID 0009-0001-8219-8078
Mohamed SaadiLaboratoire de Chimie Appliquée des Matériaux, Centre des Sciences des Matériaux, Faculty of Science, Mohammed V University in Rabat, Avenue Ibn Battouta, BP 1014, Rabat 10000, Morocco.ORCID 0000-0003-2655-0230
Lahcen El AmmariLaboratoire de Chimie Appliquée des Matériaux, Centre des Sciences des Matériaux, Faculty of Science, Mohammed V University in Rabat, Avenue Ibn Battouta, BP 1014, Rabat 10000, Morocco.ORCID 0000-0001-7980-974X
Moha BerrahoLaboratoire de Chimie des Substances Naturelles, Unité Associée au CNRST (URAC16), Faculty of Sciences Semlalia, Cadi Ayyad University, BP 2390, Marrakech 40001, Morocco.
Mohammed MerzoukiLaboratory of Applied Chemistry Environment (LCAE-ECOMP), Faculty of Science Oujda, University Mohammed First, Oujda 60000, Morocco.ORCID 0000-0003-1132-4468
Brahim BoualyMultidisciplinary Research and Innovation Laboratory, Faculté Polydisciplinaire de Khouribga, Université Sultan Moulay Slimane de Beni-Mellal, Khouribga 23000, Morocco.
Belkheir HammoutiEuromed Research Center, Euromed Polytechnic School, Euromed University of Fes, Fes 30030, Morocco.ORCID 0000-0003-3673-7904
Rachid SabbahiResearch Team in Science and Technology, Higher School of Technology, Ibn Zohr University, Laayoune 70000, Morocco.ORCID 0000-0002-8745-8799
Abdallah KarimLaboratory of Molecular Chemistry, Faculty of Sciences Semlalia, Cadi Ayyad University, BP 2390, Marrakech 40001, Morocco.ORCID 0000-0001-5389-1060
Mohammed M AlanaziDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-0483-8113
Alicia Ayerdi GotorInstitut Polytechnique UniLaSalle, AGHYLE, UP 2018.C101, UniLaSalle, 19 Rue Pierre Waguet, BP 30313, 60026 Beauvais, France.ORCID 0000-0001-6725-3334
Larbi RhaziInstitut Polytechnique UniLaSalle, Université d'Artois, ULR 7519, 19 Rue Pierre Waguet, BP 30313, 60026 Beauvais, France.ORCID 0000-0001-6489-3109

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the synthesis of two novel halogenated nitro-arylhimachalene derivatives: 2-bromo-3,5,5,9-tetramethyl-1-nitro-6,7,8,9-tetrahydro-5H-benzo[7]annulene (bromo-nitro-arylhimachalene) and 2-chloro-3,5,5,9-tetramethyl-1,4-dinitro-6,7,8,9-tetrahydro-5H-benzo[7]annulene (chloro-dinitro-arylhimachalene). These compounds were derived from arylhimachalene, an important sesquiterpene component of Atlas cedar essential oil, via a two-step halogenation and nitration process. Characterization was performed using

Indexed as

arylhimachaleneDFT calculationhalogenationmolecular dockingnitrationsesquiterpeneX-ray diffraction

Identifiers

PMID38930959
PMCPMC11206413

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.