Evidence mapPaperPMID 38930998Full record

ReviewMolecules (Basel, Switzerland)2024

Ameliorative Effects of Curcumin on Type 2 Diabetes Mellitus.

Yujin Gu, Qun Niu, Qili Zhang, Yanfang Zhao

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yujin GuSchool of Life Sciences and Medicine, Shandong University of Technology, Xincun West Road 266, Zhang Dian District, Zibo 255000, China.
Qun NiuInstitute of Xinhua Pharmaceutical, Shandong Xinhua Pharmaceutical Co., Ltd., Lutai Avenue 1, Gaoxin District, Zibo 255000, China.
Qili ZhangSchool of Life Sciences and Medicine, Shandong University of Technology, Xincun West Road 266, Zhang Dian District, Zibo 255000, China.
Yanfang ZhaoSchool of Life Sciences and Medicine, Shandong University of Technology, Xincun West Road 266, Zhang Dian District, Zibo 255000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 2 diabetes mellitus (T2DM), a multifactorial and complicated metabolic disorder, is a growing public health problem. Numerous studies have indicated that bioactive compounds from herbal medicine have beneficial effects on T2DM prevention and treatment, owing to their numerous biological properties. Curcumin, the major curcuminoid of turmeric, is one of the most studied bioactive components of herbal supplements, and has a variety of biological activities. Clinical trials and preclinical research have recently produced compelling data to demonstrate the crucial functions of curcumin against T2DM via several routes. Accordingly, this review systematically summarizes the antidiabetic activity of curcumin, along with various mechanisms. Results showed that effectiveness of curcumin on T2DM is due to it being anti-inflammatory, anti-oxidant, antihyperglycemic, anti-apoptotic, and antihyperlipidemic, among other activities. In light of these results, curcumin may be a promising prevention/treatment choice for T2DM.

Indexed as

CurcuminDiabetes Mellitus, Type 2Hypoglycemic AgentsAnimalsAnti-Inflammatory AgentsAntioxidantsHumansAnti-Inflammatory AgentsAntioxidantsCurcuminHypoglycemic Agentsantidiabetic activitycurcuminmolecular mechanismstype 2 diabetes mellitus

Identifiers

PMID38930998
PMCPMC11206386

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.