Evidence map›Paper›PMID 38931852›Full record

ArticlePharmaceutics2024

Porous Chitosan/Hydroxyapatite Composite Microspheres for Vancomycin Loading and Releasing.

Meng-Ying Wu, Yi-Ting Kuo, I-Fang Kao, Shiow-Kang Yen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Meng-Ying WuDepartment of Materials Science and Engineering, National Chung Hsing University, Taichung 402, Taiwan.
Yi-Ting KuoDepartment of Materials Science and Engineering, National Chung Hsing University, Taichung 402, Taiwan.
I-Fang KaoDepartment of Materials Science and Engineering, National Chung Hsing University, Taichung 402, Taiwan.
Shiow-Kang YenDepartment of Materials Science and Engineering, National Chung Hsing University, Taichung 402, Taiwan.ORCID 0000-0003-0242-3173

Funding

National Science and Technology Council NSTC 108-2221-E-005-029National Science and Technology Council NSTC109-2221-E-005-039National Science and Technology Council NSTC 110-2221-E-005-021National Science and Technology Council NSTC 111-2221-E-005-065National Science and Technology Council NSTC 112-2622-E-005-008
6 · The paper itself

Abstract

Porous chitosan/hydroxyapatite (Chi-HAp) composite microspheres were prepared in an aqueous solution containing chitosan, calcium nitrate, and ammonium dihydrogen phosphate by using a hydrothermal method at various temperatures. The investigation indicated that temperature significantly impacted the final product's appearance. Hydroxyapatite (HAp) coupled with dicalcium phosphate dihydrate (DCPD) flakes were obviously found at 65 and 70 °C, while the latter gradually disappeared at higher temperatures. Conversely, synthesis at 90 °C led to smaller particle sizes due to the broken chitosan chains. The microspheres synthesized at 75 °C were selected for further analysis, revealing porous structures with specific surface areas of 36.66 m

Indexed as

drug loading and releasinginhibiting zoneporous chitosan/hydroxyapatite microspheresvancomycin

Identifiers

PMID38931852
PMCPMC11206644

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.