Elucidation of Dithiol-yne Comb Polymer Architectures by Tandem Mass Spectrometry and Ion Mobility Techniques.

Kayla Williams-Pavlantos, Abdol Hadi Mokarizadeh, Brennan J Curole, Scott M Grayson, Mesfin Tsige, Chrys Wesdemiotis

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Article in Polymers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Kayla Williams-PavlantosDepartment of Chemistry, University of Akron, Akron, OH 44325, USA.

Abdol Hadi MokarizadehSchool of Polymer Science and Polymer Engineering, University of Akron, Akron, OH 44325, USA.ORCID 0000-0001-5922-7654

Brennan J CuroleDepartment of Chemistry, Tulane University, New Orleans, LA 70118, USA.

Scott M GraysonDepartment of Chemistry, Tulane University, New Orleans, LA 70118, USA.

Mesfin TsigeSchool of Polymer Science and Polymer Engineering, University of Akron, Akron, OH 44325, USA.ORCID 0000-0002-7540-2050

Chrys WesdemiotisDepartment of Chemistry, University of Akron, Akron, OH 44325, USA.ORCID 0000-0002-7916-4782

Funding

National Science Foundation CHE-1808115

6 · The paper itself

Abstract

Polymers have a wide range of applications depending on their composition, size, and architecture. Varying any of these three characteristics can greatly impact the resulting chemical, physical, and mechanical properties. While many techniques are available to determine polymer composition and size, determining the exact polymer architecture is more challenging. Herein, tandem mass spectrometry (MS/MS) and ion mobility mass spectrometry (IM-MS) methods are utilized to derive crucial architectural information about dithiol-yne comb polymers. Based on their unique fragmentation products and IM drift times, dithiol-yne oligomers with distinct architectures were successfully differentiated and characterized. Additionally, experimental collision cross-sections (Ω) derived via IM-MS were compared to theoretically extracted Ω values from molecular dynamics simulated structures to deduce the architectural motif of these comb oligomers. Overall, this work demonstrates the benefits of combining various mass spectrometry techniques in order to gain a complete understanding of a complex polymer mixture.

Indexed as

comb polymersion mobilitymolecular modelingtandem mass spectrometry

Identifiers

PMID38932016

DOI10.3390/polym16121665

PMCPMC11207239

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