Evidence map›Paper›PMID 38934799›Full record

Trial reportJournal of the American Heart Association2024

Qualifying Event and Recurrence of Ischemic Stroke in Symptomatic Artery Occlusion: A Post Hoc Analysis of CMOSS.

Guangdong Lu, Tao Wang, Xinyi Sun, Renjie Yang, Jichang Luo, Xiaoguang Tong, Yuxiang Gu, Jiyue Wang, Zhiyong Tong, Dong Kuai and 11 more

Registry-linked trialAbstract readRandomized Controlled TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01758614 (The Carotid and Middle Cerebral Artery Occlusion Surgery Study), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01758614 phase3completednot on this map

The Carotid and Middle Cerebral Artery Occlusion Surgery Study

TypeinterventionalSponsorXuanwu Hospital, BeijingRan2013 to 2020Enrolled330ConditionsCarotid Artery Occlusion, Middle Cerebral Artery Occlusion, StrokeArmsbypass surgery, Aspirin, Clopidogrel
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Guangdong LuDepartment of Neurosurgery and Interventional Neuroradiology Xuanwu Hospital, China International Neuroscience Institute, Capital Medical University, National Center for Neurological Disorders Beijing China.
Tao WangDepartment of Neurosurgery Xuanwu Hospital, China International Neuroscience Institute, Capital Medical University, National Center for Neurological Disorders Beijing China.ORCID 0000-0003-1225-0173
Xinyi SunDepartment of Neurosurgery Xuanwu Hospital, China International Neuroscience Institute, Capital Medical University, National Center for Neurological Disorders Beijing China.
Renjie YangDepartment of Neurosurgery Xuanwu Hospital, China International Neuroscience Institute, Capital Medical University, National Center for Neurological Disorders Beijing China.ORCID 0000-0003-2449-591X
Jichang LuoDepartment of Neurosurgery Xuanwu Hospital, China International Neuroscience Institute, Capital Medical University, National Center for Neurological Disorders Beijing China.ORCID 0000-0002-8341-0966
Xiaoguang TongDepartment of Neurosurgery Huanhu Hospital Tianjin China.
Yuxiang GuDepartment of Neurosurgery, Huashan Hospital Fudan University, National Center for Neurological Disorders Shanghai China.
Jiyue WangDepartment of Neurosurgery, Liaocheng People's Hospital Shandong First Medical University and Shandong Academy of Medical Sciences Liaocheng Shandong China.
Zhiyong TongDepartment of Neurosurgery The First Hospital of China Medical University Shenyang Liaoning China.
Dong KuaiDepartment of Neurosurgery The Affiliated Cardiovascular Hospital of Shanxi Medical University and Shanxi Cardiovascular Hospital Taiyuan Shanxi China.
Yiling CaiDepartment of Neurology Strategic Support Force Medical Center Beijing China.
Jun RenDepartment of Neurosurgery The Second Hospital of Lan Zhou University Lan Zhou China.
Donghai WangDepartment of Neurosurgery Qilu Hospital of Shandong University, Jinan, Qilu Hospital of Shandong University Dezhou Hospital Dezhou China.
Lian DuanDepartment of Neurosurgery The First Medical Center of Chinese People's Liberation Army (PLA) General Hospital Beijing China.
Aisha MaimaitiliDepartment of Neurosurgery The First Affiliated Hospital of Xinjiang Medical University Xinjiang China.
Chunhua HangDepartment of Neurosurgery, Nanjing Drum Tower Hospital, Neurosurgical Institute of Nanjing University Nanjing University Medical School Nanjing China.
Jiasheng YuDepartment of Neurosurgery, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.
Yan MaDepartment of Neurosurgery Xuanwu Hospital, China International Neuroscience Institute, Capital Medical University, National Center for Neurological Disorders Beijing China.ORCID 0000-0003-0427-9566
Sheng LiuDepartment of Interventional Radiology The First Affiliated Hospital With Nanjing Medical University Nanjing Jiangsu China.ORCID 0000-0002-4058-4413
Liqun JiaoDepartment of Neurosurgery and Interventional Neuroradiology Xuanwu Hospital, China International Neuroscience Institute, Capital Medical University, National Center for Neurological Disorders Beijing China.ORCID 0000-0003-4982-6295
for CMOSS investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe authors aimed to elucidate the relationship between latest ischemic event and the incidence of subsequent ischemic stroke in patients with symptomatic artery occlusion. METHODS AND

resultsWe analyzed the association between qualifying event-the latest ischemic event (transient ischemic attack [TIA] or stroke)-and the incidence of ipsilateral ischemic stroke in patients with symptomatic artery occlusion treated with medical therapy alone in CMOSS (Carotid or Middle Cerebral Artery Occlusion Surgery Study). The incidence of CMOSS primary outcomes, including any stroke or death within 30 days after randomization or ipsilateral ischemic stroke between 30 days and 2 years, between the bypass surgical and medical groups, stratified by qualifying events, was also compared. Of the 165 patients treated with medical therapy alone, 75 had a TIA and 90 had a stroke as their qualifying event. The incidence of ipsilateral ischemic stroke did not significantly differ between patients with a TIA and those with a stroke as their qualifying event (13.3% versus 6.7%,

conclusionsAmong patients with symptomatic artery occlusion and hemodynamic insufficiency, the risk of subsequent ipsilateral ischemic stroke does not appear to be lower in patients presenting with a TIA compared with those with a stroke. REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT01758614.

Indexed as

Ischemic Attack, TransientIschemic StrokeRecurrenceAgedCarotid StenosisFemaleHumansIncidenceInfarction, Middle Cerebral ArteryMaleMiddle AgedRisk FactorsTime FactorsTreatment Outcomebypass surgerycarotid artery occlusionmiddle cerebral artery occlusionqualifying eventstroketransient ischemic attack

Identifiers

PMID38934799
PMCPMC11255723

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.