Evidence map›Paper›PMID 38937101›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Endoplasmic Reticulum and Mitochondrial Calcium Handling Dynamically Shape Slow Afterhyperpolarizations in Vasopressin Magnocellular Neurons.

Matthew K Kirchner, Ferdinand Althammer, Elba Campos-Lira, Juliana Montanez, Javier E Stern

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Matthew K KirchnerCenter for Neuroinflammation and Cardiometabolic Diseases, Georgia State University, Atlanta, Georgia 30303.ORCID 0000-0001-6960-7685
Ferdinand AlthammerCenter for Neuroinflammation and Cardiometabolic Diseases, Georgia State University, Atlanta, Georgia 30303.
Elba Campos-LiraCenter for Neuroinflammation and Cardiometabolic Diseases, Georgia State University, Atlanta, Georgia 30303.
Juliana MontanezCenter for Neuroinflammation and Cardiometabolic Diseases, Georgia State University, Atlanta, Georgia 30303.
Javier E SternCenter for Neuroinflammation and Cardiometabolic Diseases, Georgia State University, Atlanta, Georgia 30303 jstern@gsu.edu.

Funding

Inverse neurovascular coupling in the hypothalamus and its role in positive feedback regulation of Vasopressin neurons in health and diseaseR01HL162575 · NHLBI · GEORGIA STATE UNIVERSITY · PI FILOSA, JESSICA A, STERN, JAVIER E · 2022 to 2025
$2.7M
DENDRITIC RELEASE OF NEUROPEPTIDES: ROLE IN BODILY HOMEOSTASISR01NS094640 · NINDS · GEORGIA STATE UNIVERSITY · PI STERN, JAVIER E · 2016 to 2020
$1.4M
Calcium-dependent autoregulation of vasopressin neurons in a rodent model of heart failure.K99HL168434 · NHLBI · GEORGIA STATE UNIVERSITY · PI KIRCHNER, MATTHEW · 2023 to 2024
$189k
NHLBI NIH HHS K99 HL168434NHLBI NIH HHS R01 HL162575NINDS NIH HHS R01 NS094640
6 · The paper itself

Abstract

Many neurons including vasopressin (VP) magnocellular neurosecretory cells (MNCs) of the hypothalamic supraoptic nucleus (SON) generate afterhyperpolarizations (AHPs) during spiking to slow firing, a phenomenon known as spike frequency adaptation. The AHP is underlain by Ca

Indexed as

CalciumEndoplasmic ReticulumMitochondriaNeuronsRats, WistarSupraoptic NucleusVasopressinsAction PotentialsAnimalsCalcium SignalingFemaleMaleRatsCalciumVasopressinsafterhyperpolarizationERhypothalamusion channelmitochondriavasopressin

Identifiers

PMID38937101
PMCPMC11270521

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.