ArticleLipids in health and disease2024
Association between triglyceride glucose index-related indices with gallstone disease among US adults.
Article in Lipids in health and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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33 citing papers in PubMed.
- Triglyceride-Glucose-Related Indexes as Risk Factors for Vision-Threatening Ocular Diseases: A Prospective UK Biobank Study.Investigative ophthalmology & visual science · 2026Article
- The association between triglyceride glucose index and its derived indices with kidney stones: a nationwide population-based study.World journal of urology · 2026Article
- Article
- Associations between lipid accumulation indices and gallstone prevalence in Chinese elderly: a community-based study in Fuzhou.BMC gastroenterology · 2026Article
- Article
- Association of triglyceride-glucose related indices with the incidence of venous thromboembolism: a nationwide prospective cohort study based on the UK Biobank.BMC cardiovascular disorders · 2026Article
- Article
- Risk stratification for gallstones based on 14 obesity and lipid-related Indices: a longitudinal cohort study of 44,030 Chinese adults.Lipids in health and disease · 2026Article
- High-fat diet, triglyceride glucose index, and gastrointestinal cancer: integrative insights from human and animal studies.Frontiers in nutrition · 2026Article
- The mediating role of depressive symptoms in the relationship between obesity-related triglyceride-glucose index and cognitive status among middle-aged and elderly adults: a large cohort study.Frontiers in psychiatry · 2026Article
- Enhanced prediction of cholecystectomy using obesity-modified TyG indices: a machine learning and SHAP-based study.European journal of medical research · 2025Article
- Association between triglyceride glucose index-related indices with gallbladder disease: a prospective cohort study in rural China.Scientific reports · 2025Article
- Triglyceride-glucose-waist circumference index: A powerful tool for metabolic dysfunction-associated steatotic liver disease.World journal of hepatology · 2025Review
- Positive association between cardiometabolic index and gallstones, with greater impact on women and those younger than 50 years: the NHANES 2017-2020 cross-sectional study.BMC public health · 2025Article
- Association of cardiometabolic index with gallstone disease and insulin resistance based on NHANES data.BMC gastroenterology · 2025Article
- Association between platelet-to-high-density lipoprotein cholesterol ratio and gallstone prevalence in the American adult population: a cross-sectional study analysis.BMC gastroenterology · 2025Article
- Association between dietary potassium intake and the prevalence of gallstones in American adults: an assessment of data from the national health and nutrition examination survey.BMC gastroenterology · 2025Article
- The development and evaluation of nine obesity-based indices for gallstones in U.S. adults.International journal of surgery (London, England) · 2025Article
- Cardiometabolic index as a predictor of gallstone incidence in U.S. adults: insights from NHANES 2017-2020.BMC gastroenterology · 2025Article
- Negative association between 15 obesity- and lipid-related indices and testosterone in adult males: a population based cross-sectional study.Lipids in health and disease · 2025Article
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6 authors.
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Abstract
backgroundTriglyceride glucose (TyG) index combined with obesity-related indicators [triglyceride glucose-body mass index (TyG-BMI), triglyceride glucose-waist to height ratio (TyG-WHtR), triglyceride glucose-waist circumference (TyG-WC)], represents emerging methodologies for assessing insulin resistance. The objective of this investigation was to explore the correlation between TyG-related indices and gallstone disease.
methodsThe study included 3740 adults from the 2017-2020 period of the National Health and Nutrition Examination Survey. TyG-BMI, TyG-WC, and TyG-WHtR were integrated as both continuous and categorical variables within the multivariate logistic model, respectively to evaluate the connection between various TyG-related indices and gallstone disease. Additionally, restriction cubic splines and subgroup analysis were employed to deepen our understanding of this relationship.
resultsWhen analyzed as continuous variables, positive correlations were observed between TyG-BMI, TyG-WC, TyG-WHtR and gallstone disease. The OR(95%CI) were 1.063(1.045,1.082) for TyG-BMI (per 10-unit), 1.026(1.018,1.034) for TyG-WC (per 10-unit) and 1.483(1.314,1.676) for TyG-WHtR (per 1-unit), respectively. When categorized into quartiles, these three TyG-related indices still show statistically significant associations with gallstone disease. Descending in order, the diagnostic capability for gallstone disease is demonstrated as follows: TyG-WHtR (AUC = 0.667), TyG-BMI (AUC = 0.647), and TyG-WC (AUC = 0.640).
conclusionThere were significantly positive associations between TyG-related indices, including TyG-BMI, TyG-WC, and TyG-WHtR, and gallstone disease. Of these indices, TyG-WHtR demonstrated the most favorable performance in identifying the risk of gallstone disease.
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