Evidence map›Paper›PMID 38938548›Full record

ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2024

Interaction of Glycemic Control and Statin Use on Diabetes-Tuberculosis Treatment Outcome: A Nested Case-Control Study.

Xiangrui Meng, Huiqiu Zheng, Jian Du, Xuemei Wang, Yanling Wang, Jing Hu, Jing Zhao, Qianqian Du, Yulong Gao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiangrui Meng *Center for Data Science in Health and Medicine, School of Public Health, Inner Mongolia Medical University, Hohhot 010110, China.ORCID https://orcid.org/0000-0001-5058-8701
Huiqiu Zheng *Center for Data Science in Health and Medicine, School of Public Health, Inner Mongolia Medical University, Hohhot 010110, China.ORCID https://orcid.org/0000-0002-9836-8318
Jian Du *Beijing Chest Hospital, Beijing Tuberculosis and Thoracic Tumor Research Institute, Capital Medical University, Beijing 101149, China.ORCID https://orcid.org/0000-0003-4648-1551
Xuemei WangCenter for Data Science in Health and Medicine, School of Public Health, Inner Mongolia Medical University, Hohhot 010110, China.ORCID https://orcid.org/0000-0003-0298-9695
Yanling WangCenter for Data Science in Health and Medicine, School of Public Health, Inner Mongolia Medical University, Hohhot 010110, China.ORCID https://orcid.org/0009-0000-6675-7290
Jing HuCenter for Data Science in Health and Medicine, School of Public Health, Inner Mongolia Medical University, Hohhot 010110, China.ORCID https://orcid.org/0009-0005-3167-4889
Jing ZhaoCenter for Data Science in Health and Medicine, School of Public Health, Inner Mongolia Medical University, Hohhot 010110, China.ORCID https://orcid.org/0009-0004-5536-8918
Qianqian DuCenter for Data Science in Health and Medicine, School of Public Health, Inner Mongolia Medical University, Hohhot 010110, China.ORCID https://orcid.org/0009-0009-8439-8063
Yulong GaoDepartment of Infectious Disease Control and Prevention, Inner Mongolia Center for Disease Control and Prevention, Hohhot 010031, China.ORCID https://orcid.org/0009-0005-1020-7632

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to explore the interaction of glycemic control and statin use on the treatment outcomes of pulmonary tuberculosis-diabetes comorbidity (PTB-DM) patients. A nested case-control study was conducted in a tuberculosis patients' cohort. We defined cases as patients who experienced unfavorable outcomes. Glycemic control was estimated at the baseline. Statin use was obtained from medical records. The multivariate logistic regression models were developed, and the interaction table invented by Andersson was adopted to analyze the interaction of glycemic control and statin use on treatment outcomes. A total of 2,047 patients were included in this study. There was a significant interaction between glycemic control and statin use on the treatment outcomes. Patients with good glycemic control and no statin use (OR = 0.464, 95% CI: 0.360-0.623) had a lower risk of unfavorable outcomes than those with poor glycemic control and statin use (OR = 0.604, 95% CI: 0.401-0.734). Patients with good glycemic control and statin use had the lowest risk of unfavorable outcomes (OR = 0.394, 95% CI: 0.264-0.521). Glycemic control in diabetes-tuberculosis treatment should be paid considerable attention. Patients can benefit from statin use even if they have poor glycemic control. Patients with good glycemic control and statin use can have the best outcomes.

Identifiers

PMID38938548
PMCPMC11211008

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.