Evidence map›Paper›PMID 38940749›Full record

ArticleAIDS research and human retroviruses2024

Comparing Gold-Standard Sanger Sequencing with Two Next-Generation Sequencing Platforms of HIV-1

David J Nolan, Jonathan DaRoza, Robin Brody, Krishna Ganta, Katherine Luzuriaga, Chris Huston, Simon Rosenthal, Susanna L Lamers, Rebecca Rose

Abstract readComparative Study
In one paragraph

Article in AIDS research and human retroviruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

David J NolanBioinfoexperts LLC, Thibodaux, Louisiana, USA.ORCID 0000-0002-9114-7002
Jonathan DaRozaBioinfoexperts LLC, Thibodaux, Louisiana, USA.
Robin BrodyMolecular Medicine, UMass Chan Medical School, Worcester, Massachusetts, USA.
Krishna GantaMolecular Medicine, UMass Chan Medical School, Worcester, Massachusetts, USA.
Katherine LuzuriagaMolecular Medicine, UMass Chan Medical School, Worcester, Massachusetts, USA.
Chris HustonBioinfoexperts LLC, Thibodaux, Louisiana, USA.
Simon RosenthalBioinfoexperts LLC, Thibodaux, Louisiana, USA.
Susanna L LamersBioinfoexperts LLC, Thibodaux, Louisiana, USA.
Rebecca RoseBioinfoexperts LLC, Thibodaux, Louisiana, USA.ORCID 0000-0002-5059-9176

Funding

University of Massachusetts Center for Clinical Science and Translational SupplementUL1TR001453 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2015 to 2024
$39.0M
Measurement and characterization of CNS and immune tissue myeloid HIV-1 reservoirsR01NS107022 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2018 to 2022
$3.3M
Advancing next-generation sequencing for optimization of rAAV productionR43FD008039 · FDA · BIOINFOEXPERTS · PI LAMERS, SUSANNA L · 2023 to 2023
$296k
FDA HHS R43 FD008039NCATS NIH HHS UL1 TR001453NINDS NIH HHS R01 NS107022
6 · The paper itself

Abstract

Our goal was to assess the accuracy of next generation sequencing (NGS) compared with Sanger. We performed single genome amplification (SGA) of HIV-1

Indexed as

High-Throughput Nucleotide SequencingHIV-1Sequence Analysis, DNAConsensus SequenceGenome, ViralHIV Envelope Protein gp160HIV InfectionsHumansHIV Envelope Protein gp160next-generation sequencingOxford NanoporePacific Biosciencessingle genome sequencing

Identifiers

PMID38940749
PMCPMC11631799

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.