SynthesisBMC oral health2024
Poor glycemic control impairs oral health in children with type 1 diabetes mellitus - a systematic review and meta-analysis.
Synthesis in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Dental caries and periodontal status in children and adolescents with type 1 diabetes mellitus: an umbrella review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Pooled it
- Association between type 1 diabetes mellitus and dental caries in children and adolescents: a meta-analysis and Mendelian randomization study.Frontiers in endocrinology · 2026Pooled it
- Impact of oral care knowledge on oral health behaviors among older residents of Nanjing: a cross-sectional study.BMC geriatrics · 2026Article
- Oral health and salivary inflammatory markers in children and adolescents with type 1 diabetes: A cross-sectional study.Journal of endocrinological investigation · 2026Article
- Association of glycemic variability and sociodemographic determinants with periodontal health in children with type 1 diabetes: a cross-sectional study from Türkiye.BMC oral health · 2026Article
- Oral health status and preventive determinants in children with type 1 diabetes: a cross-sectional comparative study.Frontiers in dental medicine · 2026Article
- Tooth Loss and Oral Health-Related Quality of Life: A Study in a Convenience Sample from Austria.Dentistry journal · 2025Article
- Oral Health-Related Quality of Life, Behaviours and Oral Manifestations in a Paediatric Population with Type I Diabetes Mellitus: A Comparative Cross-Sectional Study.Dentistry journal · 2025Article
- Periodontitis Frequently Exists in Patients with Colorectal Carcinoma and Causes Supplementary Impairment of Insulin Resistance.Metabolites · 2025Article
- An overlooked connection: oral health status in patients with chronic diseases.BMC oral health · 2025Article
- Article
- Association between Baltic sea diet and healthy Nordic diet index with risk of type 2 diabetes mellitus: a case-control study.Frontiers in endocrinology · 2025Article
- Relationship Between Type 1 Diabetes Mellitus and Dental Caries Status with Related Oral Health Indicators in Children.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Insight of the interrelationship and association mechanism between periodontitis and diabetes mellitus.Regenerative therapy · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThere are more than one million children and adolescents living with type 1 diabetes mellitus, and their number is steadily increasing. Diabetes affects oral health through numerous channels, including hyposalivation, immune suppression, and the inflammatory effect of glycation end-products. However, patients with type 1 diabetes must follow a strict sugar free diet that is proven to be carioprotective. Therefore, the aim of this systematic review and meta-analysis is to investigate whether children with type 1 diabetes have a difference in Decayed, Missing, Filled Teeth index (DMFT), salivary function, and periodontal status than children without diabetes, with an emphasis on glycemic control. MATERIALS AND
methodsPubMed, Embase and Cochrane libraries were screened for articles, using predefined search keys without any language or date restrictions. Two independent authors performed the selection procedure, extracted data from the eligible articles, carried out a manual search of the reference lists, and assessed the risk of bias using the Newcastle-Ottawa scale. Meta-analysis was performed in R using the random-effects model. Effect sizes were mean differences; subgroup analysis was performed on glycemic control.
results33 studies satisfied the eligibility criteria. 22 studies did not show a significant difference regarding the DMFT index between the diabetes and non-diabetes groups; six studies found that children living with diabetes had higher DMFT scores, compared to five studies that found significantly lower scores. Meta-analysis found no statistically significant differences in plaque, gingival, and calculus indexes, however it found significant differences in pooled DMFT indexes, and salivary flow rate. Subgroup analysis on glycemic control using DMFT values found significant differences in children with good and poor glycemic control with results of 0.26 (CI95%=-0.50; 1.03) and 1.46 (CI95%=0.57; 2.35), respectively.
conclusionsChildren with poor glycemic control face higher risk of developing caries compared to good control and non-diabetes children. Regular dental check-ups and strict control of glycemic levels are highly advised for children living with type 1 diabetes, further emphasizing the importance of cooperation between dentists and diabetologists.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.