Evidence map›Paper›PMID 38945527›Full record

ArticleJournal of gynecologic oncology2025

Cancer-field surgery for endometrial cancer by robotic peritoneal mesometrial resection and targeted compartmental lymphadenectomy (PMMR+TCL).

Paul Buderath, Tra My Dang, Rainer Kimmig

Abstract read
In one paragraph

Article in Journal of gynecologic oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Paul BuderathDepartment for Gynecology and Obstetrics, University Hospital Essen, Essen, Germany. paul.buderath@uk-essen.de.ORCID 0000-0003-0941-5635
Tra My DangDepartment for Gynecology and Obstetrics, University Hospital Essen, Essen, Germany.ORCID 0009-0006-6334-5681
Rainer KimmigDepartment for Gynecology and Obstetrics, University Hospital Essen, Essen, Germany.ORCID 0000-0003-1118-2199

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCancer-field surgery by peritoneal mesometrial resection and targeted compartmental lymphadenectomy (PMMR+TCL) for the treatment of endometrial cancer (EC) aims at optimal locoregional tumor control without the need for adjuvant radiotherapy. In a previous publication we could demonstrate the feasibility of the method and presented encouraging first oncologic data.

methodsFollowing up our 2021 publication, we present data on the treatment of EC by PMMR+TCL in much larger cohort and with longer follow-up.

resultsOne hundred and thirty-five patients with EC International Federation of Gynecology and Obstetrics (FIGO) I-IV (75.6% FIGO I) underwent cancer field surgery via PMMR+TCL for EC in the years 2016-2023. Mean follow-up in our cohort was 27.5 months (0, 83; 19.7). The procedure was feasible and safe with favorable intra-and postoperative complication rates. Even though 50.4% of patients had an indication for postoperative radiotherapy following national and international guidelines, the rate of postoperative irradiation administered was 10.4%. The overall recurrence rate was 8.1% and we observed 2 (1.5%) isolated locoregional recurrences.

conclusionOur results confirm the feasibility and safety of PMMR+TCL in EC patients. Oncologic data are very encouraging and hint at a superior locoregional control without adjuvant irradiation. Larger studies with longer follow-up will be needed to confirm these results.

Indexed as

Endometrial NeoplasmsLymph Node ExcisionRobotic Surgical ProceduresAdultAgedAged, 80 and overFeasibility StudiesFemaleHumansMiddle AgedNeoplasm Recurrence, LocalPeritoneumRetrospective StudiesCancer-Field SurgeryEndometrial CancerGynecologic Oncology, Sentinel Lymph Node BiopsyPMMRRobot Surgery

Identifiers

PMID38945527
PMCPMC11790992

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.