Evidence map›Paper›PMID 38947148›Full record

ArticleJournal of veterinary research2024

Investigation of doxycycline residues in bones after oral administration to broiler chickens.

Anna Gajda, Iwona Szymanek-Bany, Ewelina Nowacka-Kozak, Małgorzata Gbylik-Sikorska

Abstract read
In one paragraph

Article in Journal of veterinary research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anna GajdaDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Puławy, Poland.ORCID https://orcid.org/0000-0003-2895-4482
Iwona Szymanek-BanyDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Puławy, Poland.ORCID https://orcid.org/0009-0007-1391-5735
Ewelina Nowacka-KozakDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Puławy, Poland.ORCID https://orcid.org/0000-0001-9520-3027
Małgorzata Gbylik-SikorskaDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Puławy, Poland.ORCID https://orcid.org/0000-0002-7463-5792

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Chicken bones, a by-product of the poultry industry, can directly or indirectly enter the food chain. Bone meal and bone products could be sources of many contaminants. Considering the wide range of uses made of bones in the culinary and food industries, this material needs to be safe and antibiotic residue-free. To determine if such is the case, the concentration of doxycycline in chicken bones was investigated, this antimicrobial being one of the most commonly used in poultry production. Material and Methods: Ross 308 broilers were grouped into three experimental and one control group. Doxycycline was administered in drinking water at therapeutic and sub-therapeutic doses, as well as Results: Doxycycline was quantified at 135 μg/kg 22 days after the last day of antibiotic administration at therapeutic doses; 2,285 μg/kg after sub-therapeutic treatment for 27 days and 9.62 μg/kg 22 days after the end of spray application. Conclusion: High concentrations and long persistence of doxycycline in bones were found in this study. Doxycycline can contaminate all bone-derived products in the food and fertiliser industries.

Indexed as

bonesbroilersdoxycyclineUHPLC-MS/MS

Identifiers

PMID38947148
PMCPMC11210364

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.