Evidence map›Paper›PMID 38947317›Full record

ArticleFrontiers in immunology2024

Immune interactions and regulation with CD39

Adèle Silane Delorme, Alexandra Laguide, Marie Tamagne, Marion Klea Pinheiro, Léonie Cagnet, Deborah Neyrinck-Leglantier, Mehdi Khelfa, Sabine Cleophax, France Pirenne, Benoît Vingert

Abstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Adèle Silane Delorme *Univ Paris Est Creteil, Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Mondor de la Recherche Biomédicale (IMRB), Creteil, France.
Alexandra Laguide *Univ Paris Est Creteil, Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Mondor de la Recherche Biomédicale (IMRB), Creteil, France.
Marie TamagneUniv Paris Est Creteil, Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Mondor de la Recherche Biomédicale (IMRB), Creteil, France.
Marion Klea PinheiroUniv Paris Est Creteil, Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Mondor de la Recherche Biomédicale (IMRB), Creteil, France.
Léonie CagnetUniv Paris Est Creteil, Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Mondor de la Recherche Biomédicale (IMRB), Creteil, France.
Deborah Neyrinck-LeglantierUniv Paris Est Creteil, Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Mondor de la Recherche Biomédicale (IMRB), Creteil, France.
Mehdi KhelfaUniv Paris Est Creteil, Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Mondor de la Recherche Biomédicale (IMRB), Creteil, France.
Sabine CleophaxEtablissement Français du Sang, Ivry sur Seine, France.
France PirenneUniv Paris Est Creteil, Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Mondor de la Recherche Biomédicale (IMRB), Creteil, France.
Benoît VingertUniv Paris Est Creteil, Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Mondor de la Recherche Biomédicale (IMRB), Creteil, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: CD39 plays an important role in the immunoregulation and inhibition of effector cells. It is expressed on immune cells, including Tregs, and on extracellular vesicles (EVs) budding from the plasma membrane. Platelet transfusion may induce alloimmunization against HLA-I antigens, leading to refractoriness to platelet transfusion with severe consequences for patients. Tregs may play a key role in determining whether alloimmunization occurs in patients with hematologic disorders. We hypothesized that CD39 Methods: We characterized CD39 Results: We found that CD39

Indexed as

Blood PlateletsExtracellular VesiclesTetraspanin 29Antigens, CDApyraseB-LymphocytesCell CommunicationFemaleHumansMalePlatelet TransfusionT-Lymphocytes, RegulatoryAntigens, CDApyraseCD39 antigenENTPD1 protein, humanTetraspanin 29alloimmunizationCD39 ectoenzymecellular microparticlesextracellular vesiclesimmune activationimmunoregulatory moleculestransfusion

Identifiers

PMID38947317
PMCPMC11211594

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.