Evidence map›Paper›PMID 38947738›Full record

Trial reportOpen forum infectious diseases2024

A Comparison of Recruitment Methods for a Remote, Nationwide Clinical Trial for COVID-19 Treatment.

Katrina M Hartman, Barkha Patel, Via Rao, Aubrey A Hagen, Hanna G Saveraid, Regina Fricton, Samuel Lee, Andrew T Snyder, Matthew F Pullen, David R Boulware and 8 more

Registry-linked trialAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04510194 (COVID-OUT), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04510194 phase3completednot on this map

COVID-OUT: Early Outpatient Treatment for SARS-CoV-2 Infection (COVID-19)

TypeinterventionalSponsorUniversity of MinnesotaRan2021 to 2022Enrolled1,323ConditionsCovid19, SARS-CoV InfectionArmsMetformin, Placebo, Fluvoxamine, Ivermectin
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Katrina M HartmanGeneral Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA.ORCID https://orcid.org/0000-0001-6723-0423
Barkha PatelGeneral Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
Via RaoGeneral Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
Aubrey A HagenGeneral Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
Hanna G SaveraidGeneral Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
Regina FrictonGeneral Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
Samuel LeeGeneral Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
Andrew T SnyderGeneral Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
Matthew F PullenGeneral Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
David R BoulwareGeneral Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA.ORCID https://orcid.org/0000-0002-4715-0060
David M LiebovitzGeneral Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
Hrishikesh K BelaniGeneral Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA.ORCID https://orcid.org/0000-0003-1259-155X
Jacinda M NiklasGeneral Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
Thomas A MurrayGeneral Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA.ORCID https://orcid.org/0000-0003-2769-4957
Ken CohenGeneral Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA.ORCID https://orcid.org/0000-0002-6141-9142
Jennifer L ThompsonGeneral Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
Spencer M EricksonGeneral Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
Carolyn T BramanteGeneral Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA.ORCID https://orcid.org/0000-0001-5858-2080

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study describes decentralized recruitment and enrollment for a COVID-19 treatment trial, while comparing 5 primary recruitment methods: search engine ads, paid advertising within a national testing company, paid advertising within a regional testing company, electronic health record messages, and word of mouth. These are compared across patient demographics, efficiency, and cost. Clinical Trials Registration: NCT04510194.

Indexed as

decentralized clinical trialearly Covid-19 treatmentmutli-site trial

Identifiers

PMID38947738
PMCPMC11214097

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.