Evidence mapPaperPMID 38947984Full record

ArticleContemporary clinical trials communications2024

Detailed description of multidisciplinary prehabilitation in patients admitted to nerve sparring radical prostatectomy - A randomized feasibility study protocol.

Malene Blumenau Pedersen, John M Saxton, Brigitta Rasmussen Villumsen, Jørgen Bjerggaard Jensen, Sara Birch

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Article in Contemporary clinical trials communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Malene Blumenau PedersenDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.
John M SaxtonSchool of Sport, Exercise and Rehabilitation Sciences, University of Hull, Hull, UK.
Brigitta Rasmussen VillumsenDepartment of Anaesthesiology and Intensive Care, Gødstrup Hospital, Herning, Denmark.
Jørgen Bjerggaard JensenDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Sara BirchDepartment of Occupational- and Physiotherapy, Gødstrup Hospital, Gødstrup, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Localized prostate cancer treated with radical prostatectomy is highly effective, though severe side-effects are common after the surgery. Prehabilitation is an approach to optimize patient's physical and mental resources before surgery, to improve postoperative outcomes. The feasibility of a multi-modal home-based prehabilitation program, delivered using telehealth in patients awaiting radical prostatectomy is unknown. This paper describes the development of a prehabilitation program for patients awaiting radical prostatectomy. Method: A model by The Medical Research Council for developing and evaluating complex interventions (MRC Framework) was used in the development process. The Template for Intervention Description and Replication (TIDieR) checklist was applied for ensuring sufficient description of the interventions. A total of 40 patients will be randomized to either intervention or control group. Patients in the control group will follow standard care. The 4-week prehabilitation programme consists of exercise, pelvic floor exercise, sexual counseling, stress management and nutritional support. The interventions are home-based and delivered using telehealth. Feasibility outcomes will include recruitment, attrition rates, adherence, safety and suitability. Conclusion: We have developed a multimodal prehabilitation programme, which has the potential to bring tangible health benefits to men with prostate cancer awaiting radical prostatectomy. The results of the feasibility study will inform the design of a fully powered randomized controlled trial.

Indexed as

Complex interventionsPrehabilitationPreventive medicineProstate cancerSurgery

Identifiers

PMID38947984
PMCPMC11211855

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.