Evidence map›Paper›PMID 38948282›Full record

ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2024

[miR-342-3p Promotes the Proliferation, Migration, and Invasion of Clear Cell Renal Cell Carcinoma Cells by Targeted Inhibition of PPM1E].

Luonan Wang, Zhuoran Li, Jieqing Wu, Jinling Xie

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luonan Wang（ 453100） The First Ward, Department of Oncology, the First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, China.
Zhuoran Li（ 453100） The First Ward, Department of Oncology, the First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, China.
Jieqing Wu（ 453100） The First Ward, Department of Oncology, the First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, China.
Jinling Xie（ 453100） The First Ward, Department of Oncology, the First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the effects of microRNA-342-3p/Mg Methods: The gene chips GSE12105, GSE23085, GSE66271, and GSE66270 were searched, and the relationship between miR-342-3p, PPM1E, and the clinical malignant phenotypes of ccRCC was analyzed. ACHN and 769-P cells were transfected with miR-342-3p inhibitor. The effects of miR-342-3p on cell proliferation, migration, and invasion were examined. ACHN cell line with stable and high expression of miR-342-3p was constructed, and the tumorigenicity of the cell line in BALB/c nude mice was observed. The targeted relationship between miR-342-3p and Results: The expression of miR-342-3p was upregulated in ccRCC, and there were significant differences among patients with tumors of different T stages and G stages and those with different prognoses ( Conclusion: The miR-342-3p can inhibit PPM1E expression in a targeted way, and thus promotes the proliferation, migration, and invasion of ccRCC cells.

Indexed as

Carcinoma, Renal CellCell MovementCell ProliferationKidney NeoplasmsMice, Inbred BALB CMice, NudeMicroRNAsNeoplasm InvasivenessProtein Phosphatase 2CAnimalsCell Line, TumorHumansMiceMicroRNAsMIRN342 microRNA, humanProtein Phosphatase 2CClear cell renal cell carcinomaInvasionMg2+Mn2+-dependent protein phosphatase 1EMigrationmiR-342-3pProliferation

Identifiers

PMID38948282
PMCPMC11211793

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.