Evidence map›Paper›PMID 38948853›Full record

ArticlebioRxiv : the preprint server for biology2025

The effectiveness of selection in a species affects the direction of amino acid frequency evolution.

Hanon McShea, Andrew L Wheeler, Peter Goodman, Catherine Weibel, Sawsan Wehbi, Jennifer E James, Gavin Huttley, Joanna Masel

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hanon McSheaDepartment of Earth System Science, Stanford University.ORCID 0000-0002-9341-4899
Andrew L WheelerGraduate Interdisciplinary Program in Genetics, University of Arizona.
Peter GoodmanStatistics & Data Science, University of Arizona.
Catherine WeibelDepartment of Mathematics, University of Arizona.ORCID 0000-0003-1837-5209
Sawsan WehbiGraduate Interdisciplinary Program in Genetics, University of Arizona.ORCID 0000-0001-9498-9582
Jennifer E JamesDepartment of Ecology & Evolutionary Biology, University of Arizona.ORCID 0000-0003-0518-6783
Gavin HuttleyResearch School of Biology, The Australian National University.ORCID 0000-0001-7224-2074
Joanna MaselDepartment of Ecology & Evolutionary Biology, University of Arizona.ORCID 0000-0002-7398-2127

Funding

Computational and Mathematical Modeling of Biomedical SystemsT32GM132008 · NIGMS · UNIVERSITY OF ARIZONA · PI Ryan Gutenkunst, JOANNA MASEL · 2019 to 2026
$2.3M
NIGMS NIH HHS T32 GM132008
6 · The paper itself

Abstract

Nearly neutral theory predicts that species with higher effective population size

Indexed as

amino acid costcodon adaptationdrift barrierfolding stabilitymutation biasthermostabilitytrait evolution

Identifiers

PMID38948853
PMCPMC11212923

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.