Evidence map›Paper›PMID 38952435›Full record

ReviewBiological psychiatry global open science2024

Understanding Cognitive Behavioral Therapy for Psychosis Through the Predictive Coding Framework.

Julia M Sheffield, Aaron P Brinen, Brandee Feola, Stephan Heckers, Philip R Corlett

Abstract readReview
In one paragraph

Review in Biological psychiatry global open science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Metacognitive training (MCT) for psychosis: a systematic review and grade recommendations.European psychiatry : the journal of the Association of European Psychiatrists · 2025
    Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Delusional Unreality and Predictive Processing.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julia M SheffieldDepartment of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, Tennessee.
Aaron P BrinenDepartment of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, Tennessee.
Brandee FeolaDepartment of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, Tennessee.
Stephan HeckersDepartment of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, Tennessee.
Philip R CorlettDepartment of Psychiatry, Clinical Neuroscience Research Unit, Yale School of Medicine, New Haven, Connecticut.

Funding

Negative Valence Systems in SchizophreniaR01MH127018 · NIMH · VANDERBILT UNIVERSITY MEDICAL CENTER · PI FEOLA, BRANDEE, WOODWARD, NEIL D. · 2021 to 2025
$3.3M
Testing the role of belief updating in persecutory delusionsR01MH137024 · NIMH · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Julia May Sheffield · 2024 to 2026
$2.3M
Cognitive mechanisms of delusion severity throughout recovery from a psychotic episode: a computational approachK23MH126313 · NIMH · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SHEFFIELD, JULIA MAY · 2021 to 2025
$821k
NIMH NIH HHS K23 MH126313NIMH NIH HHS R01 MH127018NIMH NIH HHS R01 MH137024
6 · The paper itself

Abstract

Psychological treatments for persecutory delusions, particularly cognitive behavioral therapy for psychosis, are efficacious; however, mechanistic theories explaining why they work rarely bridge to the level of cognitive neuroscience. Predictive coding, a general brain processing theory rooted in cognitive and computational neuroscience, has increasing experimental support for explaining symptoms of psychosis, including the formation and maintenance of delusions. Here, we describe recent advances in cognitive behavioral therapy for psychosis-based psychotherapy for persecutory delusions, which targets specific psychological processes at the computational level of information processing. We outline how Bayesian learning models employed in predictive coding are superior to simple associative learning models for understanding the impact of cognitive behavioral interventions at the algorithmic level. We review hierarchical predictive coding as an account of belief updating rooted in prediction error signaling. We examine how this process is abnormal in psychotic disorders, garnering noisy sensory data that is made sense of through the development of overly strong delusional priors. We argue that effective cognitive behavioral therapy for psychosis systematically targets the way sensory data are selected, experienced, and interpreted, thus allowing for the strengthening of alternative beliefs. Finally, future directions based on these arguments are discussed.

Indexed as

Belief updatingCBTpPersecutory delusionsPredictive codingPsychotherapyVolatility

Identifiers

PMID38952435
PMCPMC11215207

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.