Evidence map›Paper›PMID 38953635›Full record

ArticlemBio2024

Sac1 links phosphoinositide turnover to cryptococcal virulence.

Elizabeth A Gaylord, Hau Lam Choy, Guohua Chen, Sydney L Briner, Tamara L Doering

Abstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The Vacuolar Protein 8 (Vac8) Homolog inJournal of fungi (Basel, Switzerland) · 2025
    Article
  5. Article
  6. A Quick reCAP: DiscoveringJournal of fungi (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Elizabeth A GaylordDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0003-3992-3526
Hau Lam ChoyDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0002-7813-4880
Guohua ChenDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Sydney L BrinerDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Tamara L DoeringDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0002-5179-7393

Funding

TRAINING PROGRAM IN CELLULAR AND MOLECULAR BIOLOGYT32GM007067 · NIGMS · WASHINGTON UNIVERSITY · PI TRUE-KROB, HEATHER L · 1985 to 2020
$20.4M
Rapid production of SARS-CoV-2 molecular clones using CRISPR-based yeast recombineeringR01AI100272 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MADHANI, HITEN D · 2012 to 2025
$11.3M
Training Program in Cellular and Molecular BiologyT32GM139774 · NIGMS · WASHINGTON UNIVERSITY · PI HEATHER L TRUE-KROB · 2021 to 2026
$6.7M
CRYPTOCOCCAL GLYCAN SYNTHESISR01AI135012 · NIAID · WASHINGTON UNIVERSITY · PI DOERING, TAMARA L · 2018 to 2022
$2.5M
Cryptococcal factors in host cell interactionsR21AI140979 · NIAID · WASHINGTON UNIVERSITY · PI DOERING, TAMARA L · 2018 to 2019
$428k
Leveraging genomic approaches to define sterol transport in Cryptococcus neoformansR21AI178330 · NIAID · WASHINGTON UNIVERSITY · PI DOERING, TAMARA L · 2023 to 2024
$428k
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) AI140979, AI135012, AI178330HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM007067NIAID NIH HHS R01 AI100272NIAID NIH HHS R01 AI135012NIAID NIH HHS R21 AI140979NIAID NIH HHS R21 AI178330NIGMS NIH HHS T32 GM007067NIGMS NIH HHS T32 GM139774
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CryptococcosisCryptococcus neoformansVirulence FactorsAnimalsFungal CapsulesFungal ProteinsGene DeletionHumansMicePhagocytesPhagocytosisPhosphatidylinositolsPhosphoric Monoester HydrolasesVirulenceFungal ProteinsPhosphatidylinositolsPhosphoric Monoester HydrolasesVirulence FactorsCryptococcus neoformansmycologyphosphatasephosphoinositidePI4PSac1virulence

Identifiers

PMID38953635
PMCPMC11323556

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.