Evidence map›Paper›PMID 38955832›Full record

ArticlePflugers Archiv : European journal of physiology2024

Alteration of Piezo1 signaling in type 2 diabetic mice: focus on endothelium and BK

Chae Eun Haam, Sooyeon Choi, Seonhee Byeon, Eun Yi Oh, Soo-Kyoung Choi, Young-Ho Lee

Abstract read
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. PIEZO channels as multimodal mechanotransducers.Biochemical Society transactions · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chae Eun HaamDepartment of Physiology, Yonsei University College of Medicine, 50 Yonseiro, Seodaemun-gu, Seoul, 03722, Korea.
Sooyeon ChoiDepartment of Physiology, Yonsei University College of Medicine, 50 Yonseiro, Seodaemun-gu, Seoul, 03722, Korea.
Seonhee ByeonDepartment of Physiology, Yonsei University College of Medicine, 50 Yonseiro, Seodaemun-gu, Seoul, 03722, Korea.
Eun Yi OhDepartment of Physiology, Yonsei University College of Medicine, 50 Yonseiro, Seodaemun-gu, Seoul, 03722, Korea.
Soo-Kyoung ChoiDepartment of Physiology, Yonsei University College of Medicine, 50 Yonseiro, Seodaemun-gu, Seoul, 03722, Korea. skchoi@yuhs.ac.
Young-Ho LeeDepartment of Physiology, Yonsei University College of Medicine, 50 Yonseiro, Seodaemun-gu, Seoul, 03722, Korea. yhlee@yuhs.ac.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Piezo1 mechanosensitive ion channel plays a important role in vascular physiology and disease. This study aimed to elucidate the altered signaling elicited by Piezo1 activation in the arteries of type 2 diabetes. Ten- to 12-week-old male C57BL/6 (control) and type 2 diabetic mice (db

Indexed as

Diabetes Mellitus, Type 2Ion ChannelsLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsMesenteric ArteriesAnimalsEndothelium, VascularMaleMiceMice, Inbred C57BLPyrazinesSignal TransductionThiadiazolesVasodilationBKCa protein, mouseIon ChannelsLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsPiezo1 protein, mousePyrazinesThiadiazolesyoda-1BKCa channelPiezo1Type 2 diabetesVasorelaxationYoda1

Identifiers

PMID38955832
PMCPMC11381481

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.