Evidence mapPaperPMID 38958546Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2024

Atypical monocyte dynamics in healthy humans in response to fasting and refeeding are distinguished by fasting HDL and postprandial cortisol.

Ryan G Snodgrass, Charles B Stephensen, Kevin D Laugero

Abstract read
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ryan G SnodgrassImmunity and Disease Prevention Research Unit, Western Human Nutrition Research Center, Agricultural Research Services, United States Department of Agriculture, Davis, California, United States.ORCID 0000-0001-9896-5297
Charles B StephensenImmunity and Disease Prevention Research Unit, Western Human Nutrition Research Center, Agricultural Research Services, United States Department of Agriculture, Davis, California, United States.
Kevin D LaugeroObesity and Metabolism Research Unit, Western Human Nutrition Research Center, Agricultural Research Services, United States Department of Agriculture, Davis, California, United States.

Funding

USDA | Agricultural Research Service (ARS) 2032-51530-026-00D
6 · The paper itself

Abstract

Monocytes are innate immune cells that are continuously produced in bone marrow which enter and circulate the vasculature. In response to nutrient scarcity, monocytes migrate back to bone marrow, where, upon refeeding, they are rereleased back into the bloodstream to replenish the circulation. In humans, the variability in monocyte behavior in response to fasting and refeeding has not been characterized. To investigate monocyte dynamics in humans, we measured blood monocyte fluctuations in 354 clinically healthy individuals after a 12-h overnight fast and at 3 and 6 h after consuming a mixed macronutrient challenge meal. Using cluster analysis, we identified three distinct monocyte behaviors.

Indexed as

FastingHydrocortisoneMonocytesPostprandial PeriodAdultAgedCholesterol, HDLFemaleHealthy VolunteersHumansLeukocyte CountLipoproteins, HDLMaleMiddle AgedYoung AdultCholesterol, HDLHydrocortisoneLipoproteins, HDLcortisolfastingHDLmonocytepostprandial

Identifiers

PMID38958546
PMCPMC11427091

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.