Evidence map›Paper›PMID 38960019›Full record

ReviewBiological psychiatry2024

Prescription Digital Therapeutics: An Emerging Treatment Option for Negative Symptoms in Schizophrenia.

Daniel Fulford, Lisa A Marsch, Abhishek Pratap

Abstract readReview
In one paragraph

Review in Biological psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Daniel FulfordSargent College of Health & Rehabilitation Sciences, Boston University, Boston, Massachusetts; Psychological & Brain Sciences, Boston University, Boston, Massachusetts. Electronic address: dfulford@bu.edu.
Lisa A MarschCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire.
Abhishek PratapBoehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut; Department of Biomedical Informatics and Medical Education, School of Medicine, University of Washington, Seattle, Washington; Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom; School of Medicine, Anatomy & Neurobiology, Boston University, Boston, Massachusetts.

Funding

Project-003UG1DA013035 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Aimee N Campbell, Jennifer McNeely · 2015 to 2026
$130.3M
Suicide Prediction and Prevention for People at Risk for Opioid Use DisorderUG1DA040316 · NIDA · HENNEPIN HEALTHCARE RESEARCH INSTITUTE · PI GAVIN BART · 2015 to 2026
$42.2M
Project-002UG1DA040309 · NIDA · DARTMOUTH COLLEGE · PI Lisa A. Marsch · 2015 to 2026
$37.9M
Treatment Development & Evaluation CoreP30DA029926 · NIDA · DARTMOUTH COLLEGE · PI Lisa A. Marsch · 2011 to 2026
$21.5M
Long-acting buprenorphine vs. naltrexone opioid treatments in CJS-involved adultsU01DA047982 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FARABEE, DAVID J, GRYCZYNSKI, JAN · 2019 to 2024
$20.3M
Integrated telehealth intervention to reduce chronic pain and unhealthy drinking among people living with HIVP01AA029546 · NIAAA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HEEREN, TIMOTHY C. · 2021 to 2025
$7.4M
Training in the Science of Co-Occurring DisordersT32DA037202 · NIDA · DARTMOUTH COLLEGE · PI Lisa A. Marsch · 2014 to 2026
$4.7M
Supplement: Neurobehavioral mechanisms of social isolation and loneliness in serious mental illnessR01MH127265 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI FULFORD, DANIEL C, HOLT, DAPHNE J · 2021 to 2025
$4.0M
Stable and dynamic neurobehavioral phenotypes of social isolation and loneliness in serious mental illnessR01MH125426 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI DANIEL C FULFORD, DAPHNE J HOLT · 2022 to 2026
$1.3M
SCH: INT: Collaborative Research: Passive sensing of social isolation: A digital phenotying approach R01MH122367 · NIMH · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI BUSSO, CARLOS ALBERTO, FULFORD, DANIEL C · 2019 to 2022
$1.2M
Modeling Dimensions of Individual Variation in Adaptive Foraging DecisionsR21MH124095 · NIMH · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI FULFORD, DANIEL C, MCGUIRE, JOSEPH T. · 2021 to 2022
$454k
Clarifying the relations among youth technology use, substance use and mental health.R21DA057535 · NIDA · DARTMOUTH COLLEGE · PI BORODOVSKY, JACOB T · 2022 to 2023
$451k
NIAAA NIH HHS P01 AA029546NIDA NIH HHS P30 DA029926NIDA NIH HHS R21 DA057535NIDA NIH HHS T32 DA037202NIDA NIH HHS U01 DA047982NIDA NIH HHS UG1 DA013035NIDA NIH HHS UG1 DA040309NIDA NIH HHS UG1 DA040316NIMH NIH HHS R01 MH122367NIMH NIH HHS R01 MH125426NIMH NIH HHS R01 MH127265NIMH NIH HHS R21 MH124095
6 · The paper itself

Abstract

Digital therapeutics-web-based programs, smartphone applications, and wearable devices designed to prevent, treat, or manage clinical conditions through software-driven, evidence-based intervention-can provide accessible alternatives and/or may supplement standard care for patients with serious mental illnesses, including schizophrenia. In this article, we provide a targeted summary of the rapidly growing field of digital therapeutics for schizophrenia and related serious mental illnesses. First, we define digital therapeutics. Then, we provide a brief summary of the emerging evidence of the efficacy of digital therapeutics for improving clinical outcomes, focusing on potential mechanisms of action for addressing some of the most challenging problems, including negative symptoms of psychosis. Our focus on these promising targets for digital therapeutics, including the latest in prescription models in the commercial space, highlights future directions for research and practice in this exciting field.

Indexed as

Mobile ApplicationsSchizophreniaHumansSmartphoneTelemedicineWearable Electronic DevicesDigital healthDigital therapeuticsMobile healthPsychosisPsychosocial treatmentsSchizophrenia

Identifiers

PMID38960019
PMCPMC11410508

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.