ArticleAsia Pacific journal of clinical nutrition2024
Elevated remnant cholesterol was associated with the increased metabolically unhealthy obesity risk in Chinese youth.
Article in Asia Pacific journal of clinical nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Exploring the relationship between residual cholesterol, body mass index, and hypertension risk: a national cohort study.Lipids in health and disease · 2025Observational
- Remnant cholesterol in obesity phenotypes: results from NHANES.Lipids in health and disease · 2025Article
- Remnant cholesterol elevates hyperuricemia risk in the middle aged and elderly Chinese: a longitudinal study.Scientific reports · 2024Article
- What is in a name and other peeves.Journal of diabetes · 2024Article
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5 authors.
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Abstract
BACKGROUND AND
objectivesMetabolically unhealthy obesity is characterized by the presence of cardiovascular metabolic risks such as hypertension, dyslipidemia, and hyperglycemia. Research has shown a correlation between remnant cholesterol (RC) concentrations and abdominal obesity in children. However, the effect of RC concentration on metabolically unhealthy obesity remains unclear. METHODS AND STUDY
designThis study included 3114 Chinese adolescents who received health check-ups. We used logistic regression models and receiver operating characteristic analysis to evaluate the correlation between RC concentration and metabolically unhealthy obesity in a cross-sectional design.
resultsAfter controlling for possible confounding variables, we found that individuals in the top and fourth quintiles of RC concentrations had a significantly higher likelihood of developing metabolically unhealthy obesity compared to those in the bottom quintile (ORs, 4.810 and 1.836; 95% CIs, 3.209-7.212 and 1.167-2.890, respectively). The risk of metabolically unhealthy obesity tended to increase with RC concentration (ptrend<0.001). In addition, boys showed positive associations between RC concentration and both BMI (r = 0.305, p<0.001) and waist circumference (r = 0.306, p<0.001). According to the analysis, the predictive accuracy of metabolically unhealthy obesity was 0.736 (95% CI, 0.690-0.781) for boys and 0.630 (95% CI, 0.573-0.687) for girls. The ideal prediction threshold was 0.66 for boys and 0.59 for girls.
conclusionsOur findings indicate that elevated RC concen-tration is linked to a higher likelihood of developing metabolically unhealthy obesity in young individuals, regardless of other known risk factors.
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