Evidence map›Paper›PMID 38966513›Full record

ArticleJournal of community hospital internal medicine perspectives2024

Outcome Comparison in Hospitalized COVID-19 Patients With and Without AKI.

Sanjivani Shrestha, Yani Zhang, Wajehe Najafi, Abraham Halik, JiLing Chou, Man K Michael Siu, Monika Dhillon, David S Weisman

Abstract read
In one paragraph

Article in Journal of community hospital internal medicine perspectives, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sanjivani Shrestha *Department of Nephrology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Yani Zhang *Department of Medicine, MedStar Union Memorial Hospital, Baltimore, MD, USA.
Wajehe NajafiDepartment of Medicine, MedStar Union Memorial Hospital, Baltimore, MD, USA.
Abraham HalikDepartment of Medicine, MedStar Union Memorial Hospital, Baltimore, MD, USA.
JiLing ChouDepartment of Biostatistics and Biomedical Informatics, MedStar Health Research Institute, Hyattsville, MD, USA.
Man K Michael SiuDepartment of Nephrology, University of California, Irvine, CA, USA.
Monika DhillonDepartment of Nephrology, MedStar Union Memorial Hospital, Baltimore, MD, USA.
David S WeismanDepartment of Medicine, MedStar Union Memorial Hospital, Baltimore, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Patients hospitalized with COVID-19 have a higher incidence of Acute Kidney Injury (AKI) compared with non-COVID patients. Previous observational studies showed AKI in hospitalized patients with COVID-19 was associated with significant increased mortality rate. We conducted a retrospective cohort study in a large mid-Atlantic health system to investigate whether COVID-19 associated AKI during hospitalization would lead to worse outcomes in a predominant Black patient population, compared to COVID-19 without AKI. Methods: We reviewed health records of patients (aged≥18 years) admitted with symptomatic COVID-19 between March 5, 2020, and Jun 3, 2020, in 9 acute care facilities within the MedStar Health system. Patients were followed up until 3 months after discharge. Primary outcome was inpatient mortality. Secondary outcomes were need for ICU level of care, need for intubation, length of ICU stay, length of hospital stay, need for renal replacement therapy, recovery of renal function. Results: Among 1107 patients admitted with symptomatic COVID-19, the AKI incidence rate was 35 %. African American patients made up 63 % of the total patient population and 74 % of the total AKI population. Inpatient mortality in the AKI group and the non-AKI group was 163 (41.9 %) and 71 (9.9 %), respectively. COVID-19 patients with AKI had significant higher risk of in-patient mortality (OR, 4.71 [95 % CI, 3.38-6.62], P < 0.001), ICU admission (OR, 4.27 [95 % CI, 3.21-5.72], P < 0.001) and need of intubation (OR, 6.18 [95 % CI, 4.45-8.68], P < 0.001). Conclusions: AKI in hospitalized patients with COVID-19 was associated with higher mortality rate, need for intubation and ICU admission compared to COVID-19 patients without AKI group.

Indexed as

Acute kidney injuryCovid-19Intensive care unitsMortality

Identifiers

PMID38966513
PMCPMC11221445

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.