Evidence mapPaperPMID 38969802Full record

ArticleCell research2024

Bitter taste receptor TAS2R14 activation and G protein assembly by an intracellular agonist.

Lele Tao, Dongxue Wang, Qingning Yuan, Fenghui Zhao, Yu Zhang, Tianyuan Du, Shiyi Shen, H Eric Xu, Yi Li, Dehua Yang and 1 more

Abstract readLetter
In one paragraph

Article in Cell research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Many ligands and states of bitter taste GPCRs.Nature structural & molecular biology · 2026
    Article
  4. Ligand binding modes of the bitter taste receptor T2R14 and T2R46.Nature structural & molecular biology · 2026
    Article
  5. Article
  6. Intracellular and dual-site inhibition of a bitter taste GPCR.Cellular and molecular life sciences : CMLS · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Bitter taste receptors.Chemical senses · 2025
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lele Tao *Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, Guangdong, China.
Dongxue Wang *Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, Guangdong, China.
Qingning Yuan *College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Fenghui Zhao *State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Yu ZhangZhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, Guangdong, China.
Tianyuan DuSchool of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Shiyi ShenState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
H Eric XuState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. eric.xu@simm.ac.cn.ORCID http://orcid.org/0000-0002-6829-8144
Yi LiZhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, Guangdong, China. liyi@simm.ac.cn.
Dehua YangState Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. dhyang@simm.ac.cn.ORCID http://orcid.org/0000-0003-3028-3243
Jia DuanZhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, Guangdong, China. duanjia@simm.ac.cn.ORCID http://orcid.org/0000-0002-3605-046X

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82373881
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Receptors, G-Protein-CoupledAnimalsGTP-Binding ProteinsHEK293 CellsHumansTasteGTP-Binding ProteinsReceptors, G-Protein-Coupled

Identifiers

PMID38969802
PMCPMC11442968

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.