Evidence map›Paper›PMID 38971192›Full record

ArticleJournal of affective disorders2024

The influence of neuropeptide Y (NPY) on the relationship between emotion regulation and mood-related pathology in survivors of childhood interpersonal trauma.

Sarah K Stevens, Randy Boley, Mark Pollack, Stevan Hobfoll, Stewart Shankman, Linzy Pinkerton, Zerbrina Valdespino-Hayden, Angela C Glover, Michelle Kaufman, Sheila Dowd and 1 more

Abstract read
In one paragraph

Article in Journal of affective disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sarah K StevensDepartment of Psychological Science, University of California, Irvine, Irvine, CA, United States of America.
Randy BoleyDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, United States of America; Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, United States of America.
Mark PollackDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, United States of America.
Stevan HobfollDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, United States of America; STAR: Stress, Anxiety and Resilience Consultants, Sandy, UT, United States of America.
Stewart ShankmanDepartment of Psychiatry and Behavioral Sciences, Northwestern University, Chicago, IL, United States of America.
Linzy PinkertonDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, United States of America; Department of Psychiatry and Behavioral Sciences, Northwestern University, Chicago, IL, United States of America.
Zerbrina Valdespino-HaydenDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, United States of America; VA North Texas Health Care System, Fort Worth, TX, United States of America.
Angela C GloverDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, United States of America; Psychology Department, Fordham University, Bronx, NY, United States of America.
Michelle KaufmanDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, United States of America; Department of Psychology, The University of Memphis, Memphis, TN, United States of America.
Sheila DowdDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, United States of America.
Alyson K ZaltaDepartment of Psychological Science, University of California, Irvine, Irvine, CA, United States of America; Department of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, United States of America. Electronic address: azalta@uci.edu.

Funding

Using CBT to Probe Psychobiobehavioral Resilience to Post-trauma PsychopathologyK23MH103394 · NIMH · RUSH UNIVERSITY MEDICAL CENTER · PI ZALTA, ALYSON KAY · 2014 to 2018
$769k
NIMH NIH HHS K23 MH103394
6 · The paper itself

Abstract

Neuropeptide Y (NPY) is a 36-amino acid peptide that is widely expressed throughout the limbic system. Recent evidence has highlighted NPY as a marker of resilience to posttraumatic psychopathology, which may be due to its association with neural regions involved with emotion regulation. This study examined whether plasma NPY levels moderated the relationship between emotion regulation and psychopathology in a sample of adult survivors of childhood interpersonal trauma, a population known to be at high risk for psychopathology. Adults exposed to an interpersonal criterion A trauma during childhood (N = 54) were recruited from an urban population at a midwestern medical center and completed a baseline study visit as part of a larger clinical trial. Participants gave a blood sample in order to assess circulating levels of NPY and answered questions related to emotion regulation and mood-related pathology. Results of a moderated multiple regression showed that the overall model was significant R

Indexed as

Emotional RegulationNeuropeptide YAdultAdverse Childhood ExperiencesAffectFemaleHumansInterpersonal RelationsMaleMiddle AgedMood DisordersStress Disorders, Post-TraumaticSurvivorsYoung AdultNeuropeptide YAnxietyBiomarkerDepressionEmotion regulationNeuropeptide-YPosttraumatic stress

Identifiers

PMID38971192
PMCPMC11460676

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.