Evidence map›Paper›PMID 38972687›Full record

ReviewHand clinics2024

Interpretation of Data from Translational Rodent Nerve Injury and Repair Models.

Evan B Marsh, Alison K Snyder-Warwick, Susan E Mackinnon, Matthew D Wood

Abstract readReview
In one paragraph

Review in Hand clinics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Evan B MarshDivision of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St Louis, MO 63110, USA.
Alison K Snyder-WarwickDivision of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St Louis, MO 63110, USA.
Susan E MackinnonDivision of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St Louis, MO 63110, USA.
Matthew D WoodDivision of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St Louis, MO 63110, USA. Electronic address: woodmd@wustl.edu.

Funding

T cell roles in regeneration across nerve graft alternativesR01NS115960 · NINDS · WASHINGTON UNIVERSITY · PI WOOD, MATTHEW D. · 2020 to 2024
$1.8M
NINDS NIH HHS R01 NS115960
6 · The paper itself

Abstract

This article highlights the use of rodents as preclinical models to evaluate the management of nerve injuries, describing the pitfalls and value from rodent nerve injury and regeneration outcomes, as well as treatments derived from these rodent models. The anatomic structure, size, and cellular and molecular differences and similarities between rodent and human nerves are summarized. Specific examples of success and failure when assessing outcome metrics are presented for context. Evidence for translation to clinical practice includes the topics of electrical stimulation, Tacrolimus (FK506), and acellular nerve allografts.

Indexed as

Disease Models, AnimalNerve RegenerationPeripheral Nerve InjuriesAnimalsElectric Stimulation TherapyHumansImmunosuppressive AgentsMiceRatsRodentiaTacrolimusTranslational Research, BiomedicalImmunosuppressive AgentsTacrolimusFunctionHistologyPeripheral nerveRatRegeneration

Identifiers

PMID38972687
PMCPMC11228394

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.