Evidence map›Paper›PMID 38974133›Full record

ArticleGalen medical journal2023

The Regulation of Pyroptosis and Ferroptosis by MicroRNAs in Cardiovascular Diseases.

Akram Shariati, Venus Shahabi Raberi, Mehdi Masumi, Ali Tarbiat, Elham Rastgoo, Reza Faramarz Zadeh

Abstract read
In one paragraph

Article in Galen medical journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Akram ShariatiDepartment of Cardiology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Venus Shahabi RaberiSeyed-Al-Shohada Cardiology Hospital, Urmia University of Medical Sciences, Urmia, Iran.
Mehdi MasumiSeyed-Al-Shohada Cardiology Hospital, Urmia University of Medical Sciences, Urmia, Iran.
Ali TarbiatSeyed-Al-Shohada Cardiology Hospital, Urmia University of Medical Sciences, Urmia, Iran.
Elham RastgooDepartment of Radiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Reza Faramarz ZadehSeyed-Al-Shohada Cardiology Hospital, Urmia University of Medical Sciences, Urmia, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases (CVDs) are considered the most prevalent noncommunicable disease and the leading cause of death worldwide. A plethora of evidence has revealed that microRNAs (miRNAs) could control the inhibition or progression of CVDs by regulating pivotal cell processes ranging from metabolism and homeostasis to programmed cell death (PCD). Pyroptosis and ferroptosis are two major types of nonapoptotic PCDs involved in the pathogenesis of heart failure. However, no study has discussed the crosstalk between miRNAs and these two types of PCDs in the CVDs. The current review demonstrated that different types of miRNAs can regulate both ferroptosis and pyroptosis and thereby affect CVDs progression and inhibition. Altogether, the discussed content encourages further studies to confirm that mentioned pathways are suitable to be considered as novel therapeutic approaches against CVDs.

Indexed as

Cardiovascular DiseasesFerroptosisHeart FailureMiRNAsPyroptosis

Identifiers

PMID38974133
PMCPMC11227648

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.