Evidence map›Paper›PMID 38974511›Full record

ArticleClinical interventions in aging2024

Potentially Inappropriate Use of Medication and Its Determinants Among Ambulatory Older Adults in Six Community Chain Pharmacies in Asmara, Eritrea: A Cross-Sectional Study Using the 2023 American Geriatric Society Beers Criteria

Saleh Idrisnur, Nuru Abdu, Filipos Yohannes, Tomas Tewelde, Natnael Russom, Eyasu H Tesfamariam

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Article in Clinical interventions in aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Saleh IdrisnurProduct Evaluation and Registration Unit, National Medicine and Food Administration, Ministry of Health, Asmara, Eritrea.ORCID 0000-0002-8007-1153
Nuru AbduDepartment of Pharmacy, Adi-Tekelezan Community Hospital, Ministry of Health, Adi-Tekelezan, Eritrea.ORCID 0000-0003-2426-4337
Filipos YohannesDepartment of Pharmacy, Ghindae Zonal Referral Hospital, Ministry of Health, Ghindae, Eritrea.ORCID 0000-0003-1085-8142
Tomas TeweldeGash-Barka Zonal Pharmaceutical Services, Ministry of Health, Barentu, Eritrea.ORCID 0009-0009-9671-4983
Natnael RussomEritrean Pharmacovigilance Center, National Medicine and Food Administration, Ministry of Health, Asmara, Eritrea.ORCID 0000-0002-4333-2932
Eyasu H TesfamariamBiostatistics and Epidemiology, Department of Statistics, College of Sciences, Mai-Nefhi, Eritrea.ORCID 0000-0002-8462-0500

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Potentially inappropriate medication (PIM) use is one of the main drug-related problems encountered in older adults. It is associated with adverse drug events, morbidity, mortality, increased economic costs, and negative effects on the quality of life that requires strict monitoring of prescriptions in older adults. Thus, the study aimed to assess potentially inappropriate medication use and its determinants among older adults. Methods: A cross-sectional study was conducted among all outpatient prescriptions dispensed to older adults (aged 65 years and above) in six community chain pharmacies in Asmara, Eritrea. Data were collected retrospectively, between June 16 and July 16, 2023. PIMs were detected using the 2023 American Geriatric Society (AGS) Beers Criteria Results: A total of 2680 outpatient prescriptions dispensed to older adults were included in this study. The prevalence of PIM among prescriptions was 18.1% (95% CI: 16.7, 19.6). Moreover, a total of 470 medications were found to be avoided in older adults. The most commonly prescribed PIMs were sulfonylureas (27.2%) and substituted alkylamines (16.2%). The prevalence of prescriptions containing medications to be used with caution in older adults was 13.2% (95% CI: 12.0, 14.5). Age (Adjusted Odds Ratio (AOR))=0.98, 95% CI: 0.97, 0.99), polypharmacy (AOR=2.77, 95% CI: 1.49, 5.15), and general practitioner prescriber (AOR=1.38, 95% CI: 1.11, 1.70) were significantly associated with PIMs. Conclusion: A considerable number of ambulatory older adults were exposed to PIMs which require a close attention by policymakers, program managers, and healthcare professionals.

Indexed as

Inappropriate PrescribingPotentially Inappropriate Medication ListAgedAged, 80 and overCross-Sectional StudiesEritreaFemaleHumansLogistic ModelsMalePharmaciesPolypharmacyPrevalenceRetrospective StudiesAGS Beers Criteria®community chain pharmacydeterminantsEritreaolder adultspotentially inappropriate medications

Identifiers

PMID38974511
PMCPMC11227139

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.