Evidence map›Paper›PMID 38974517›Full record

ArticleFrontiers in physiology2024

Lysosomal TRPML1 triggers global Ca

Valentina Brunetti, Roberto Berra-Romani, Filippo Conca, Teresa Soda, Gerardo Rosario Biella, Andrea Gerbino, Francesco Moccia, Giorgia Scarpellino

Abstract read
In one paragraph

Article in Frontiers in physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Autophagy-lysosomal pathway in neurodegeneration.Molecular neurodegeneration advances · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. CaBiomedicines · 2025
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Valentina BrunettiLaboratory of General Physiology, Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, Pavia, Italy.
Roberto Berra-RomaniDepartment of Biomedicine, School of Medicine, Benemérita Universidad Autónoma de Puebla, Puebla, Mexico.
Filippo ConcaDepartment of Molecular Medicine, University of Pavia, Pavia, Italy.
Teresa SodaDepartment of Health Sciences, University of Magna Graecia, Catanzaro, Italy.
Gerardo Rosario BiellaLaboratory of General Physiology, Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, Pavia, Italy.
Andrea GerbinoDepartment of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari "Aldo Moro", Bari, Italy.
Francesco MocciaDepartment of Medicine and Health Sciences "V. Tiberio", University of Molise, Campobasso, Italy.
Giorgia ScarpellinoLaboratory of General Physiology, Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, Pavia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lysosomal Ca

Indexed as

Ca2+ signalingendothelial cellsInsP3 receptorslysosomesnitric oxidestore-operated Ca2+ entryTRPML1

Identifiers

PMID38974517
PMCPMC11224436

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.