Evidence map›Paper›PMID 38977355›Full record

SynthesisBMJ paediatrics open2024

Physical health complications in children and young people with avoidant restrictive food intake disorder (ARFID): a systematic review and meta-analysis.

Rachel Marie James, Jonathan O'Shea, Nadia Micali, Simon J Russell, Lee D Hudson

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMJ paediatrics open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Quality of Life in Adults with Eating Disorders.Behavioral sciences (Basel, Switzerland) · 2026
    Article
  4. Prevalence of Avoidant/Restrictive Food Intake Disorder (ARFID) in children with and without food allergy.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rachel Marie JamesUCL GOS Institute of Child Health, London, UK rachel.james.22@ucl.ac.uk.ORCID http://orcid.org/0009-0001-6135-7324
Jonathan O'SheaUCL GOS Institute of Child Health, London, UK.ORCID http://orcid.org/0009-0007-5187-2465
Nadia MicaliUCL GOS Institute of Child Health, London, UK.ORCID http://orcid.org/0000-0001-5571-2273
Simon J RussellUCL GOS Institute of Child Health, London, UK.ORCID http://orcid.org/0000-0001-9447-1169
Lee D HudsonUCL GOS Institute of Child Health, London, UK.ORCID http://orcid.org/0000-0003-0883-8791

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAvoidant restrictive food intake disorder (ARFID) is a feeding and eating disorder with known acute and longstanding physical health complications in children and young people (CYP) and commonly presents to paediatricians.

objectiveTo systematically review the published literature on physical health complications in CYP with ARFID using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.

methodsA systematic search of PubMed, Embase, Web of Science, PsycINFO and Cochrane Library was performed on 14 February 2024. Studies reporting physical health complications in CYP ≤25 years with ARFID were included. We pooled studies for meta-analysis comparing ARFID with healthy controls or anorexia nervosa (AN).

resultsOf 9058 studies found in searches, we included 132 studies. We found evidence for low weight, nutritional deficiencies and low bone mineral density. CYP with ARFID can present across the weight spectrum; however, the majority of CYP with ARFID were within the healthy weight to underweight range. Most studies reported normal range heart rates and blood pressures in ARFID, but some CYP with ARFID do experience bradycardia and hypotension. CYP with ARFID had higher heart rates than AN (weighted mean difference: 12.93 bpm; 95% CI: 8.65 to 17.21; n=685); heterogeneity was high (I

conclusionThere is a broad range of physical health complications associated with ARFID requiring clinical consideration. Many CYP with ARFID are not underweight yet still have complications. Less cardiovascular complications found in ARFID compared with AN may be related to chronicity. PROSPERO REGISTRATION NUMBER: CRD42022376866.

Indexed as

Avoidant Restrictive Food Intake DisorderAdolescentChildHumansYoung AdultAdolescent HealthChild HealthPsychology

Identifiers

PMID38977355
PMCPMC11261741

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.