Evidence mapPaperPMID 38978009Full record

ArticleBMC geriatrics2024

Multidisciplinary medication review during older patient hospitalization according to STOPP/START criteria reduces potentially inappropriate prescriptions: MoPIM cohort study.

Sara Ortonobes, Susana Herranz, Marina Lleal, Daniel Sevilla-Sánchez, Rosa Jordana, Oscar Mascaró, Olivia Ferrández, Elisabet de Jaime, Rafael Estrada, Gloria Julia Nazco and 2 more

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in BMC geriatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02830425 (Potentially Inappropriate Prescription Associated to Multimorbidity, Using the Explicit STOPP-START), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02830425 completednot on this map

Potentially Inappropriate Prescription Associated to Multimorbidity, Using the Explicit STOPP-START (Screening Tool of Older Persons' Potentially Inappropriate Prescriptions/Screening Tool to Alert Doctors to the Right Treatment) Criteria

TypeobservationalSponsorCorporacion Parc TauliRan2016 to 2019Enrolled740ConditionsChronic DiseaseArmsNo intervention
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sara OrtonobesPharmacy Department, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí (I3PT-CERCA), Universitat Autònoma de Barcelona, 08208, Sabadell, Spain. sortonobes@tauli.cat.
Susana HerranzAcute Care Geriatric Unit, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí (I3PT-CERCA), Universitat Autònoma de Barcelona, 08208, Sabadell, Catalonia, Spain.
Marina LlealClinical Epidemiology and Cancer Screening Department, Parc Taulí Hospital Universitari, Institut d'Investigació I Innovació Parc Taulí (I3PT-CERCA), Universitat Autònoma de Barcelona, 08208, Sabadell, Spain.
Daniel Sevilla-SánchezPharmacy Department, Parc Sanitari Pere Virgili, 08023, Barcelona, Spain.
Rosa JordanaInternal Medicine Department, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí (I3PT-CERCA), Universitat Autònoma de Barcelona, 08208, Sabadell, Spain.
Oscar MascaróInternal Medicine Department, University Hospital of Vic, Multidisciplinary Inflamation Research Group (MIRG), Facultat de Medicina, Universitat de Vic, Universitat Central de Catalunya, 08500, Vic, Spain.
Olivia FerrándezPharmacy Department, Consorci Parc de Salut Mar, 08003, Barcelona, Spain.
Elisabet de JaimeGeriatrics Department, Consorci Parc de Salut Mar, 08003, Barcelona, Spain.
Rafael EstradaInternal Medicine, Hospital Galdakao-Usansolo, 48960, Galdakao, Spain.
Gloria Julia NazcoPharmacy Department, Hospital Universitario de Canarias, 38320, La Laguna, Spain.
Marisa BaréResearch Network On Health Services in Chronic Patients (REDISSEC), Instituto de Salud Carlos III, 28029, Madrid, Spain. mbare@tauli.cat.
MoPIM Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMultimorbidity and polypharmacy in older adults converts the detection and adequacy of potentially inappropriate drug prescriptions (PIDP) in a healthcare priority. The objectives of this study are to describe the clinical decisions taken after the identification of PIDP by clinical pharmacists, using STOPP/START criteria, and to evaluate the degree of accomplishment of these decisions.

methodsMulticenter, prospective, non-comparative cohort study in patients aged 65 and older, hospitalized because of an exacerbation of their chronic conditions. Each possible PIDP was manually identified by the clinical pharmacist at admission and an initial decision was taken by a multidisciplinary clinical committee. At discharge, criteria were re-applied and final decisions recorded.

resultsFrom all patients (n = 674), 493 (73.1%) presented at least one STOPP criteria at admission, significantly reduced up to 258 (38.3%) at discharge. A similar trend was observed for START criteria (36.7% vs. 15.7%). Regarding the top 10 most prevalent STOPP criteria, the clinical committee initially agreed to withdraw 257 (34.2%) prescriptions and to modify 93 (12.4%) prescriptions. However, the evaluation of final clinical decisions revealed that 503 (67.0%) of those STOPP criteria were ultimately amended. For the top 10 START criteria associated PIDP, the committee decided to initiate 149 (51.7%) prescriptions, while a total of 198 (68.8%) were finally introduced at discharge.

conclusionsThe clinical committee, through a pharmacotherapy review, succeeded in identifying and reducing the degree of prescription inadequacy, for both STOPP and START criteria, in older patients with high degree of multimorbidity and polypharmacy.

trial registrationNCT02830425.

Indexed as

HospitalizationInappropriate PrescribingPotentially Inappropriate Medication ListAgedAged, 80 and overCohort StudiesFemaleHumansMalePatient Care TeamPolypharmacyProspective StudiesClinical committee reviewMultimorbidityOlder adultsPolypharmacyPotentially inappropriate prescriptionPrescription adequacy

Identifiers

PMID38978009
PMCPMC11232270

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.