Evidence map›Paper›PMID 38978600›Full record

ArticleResearch square2024

Idiosyncratic nature of lactation reveals link to breast cancer risk.

Mrittika Chattopadhyay, Edmund Charles Jenkins, William Janssen, Thelma Mashaka, Doris Germain

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Mrittika ChattopadhyayIcahn School of Medicine at Mount Sinai, Tisch Cancer Institute, Department of Medicine, Division of Hematology/ Oncology, New York, 10029, NY, USA.
Edmund Charles JenkinsIcahn School of Medicine at Mount Sinai, Tisch Cancer Institute, Department of Medicine, Division of Hematology/ Oncology, New York, 10029, NY, USA.
William JanssenIcahn School of Medicine at Mount Sinai, Microscopy and Advanced Bioimaging Core, New York, 10029, NY, USA.
Thelma MashakaIcahn School of Medicine at Mount Sinai, Tisch Cancer Institute, Department of Medicine, Division of Hematology/ Oncology, New York, 10029, NY, USA.
Doris GermainIcahn School of Medicine at Mount Sinai, Tisch Cancer Institute, Department of Medicine, Division of Hematology/ Oncology, New York, 10029, NY, USA.ORCID https://orcid.org/0000-0001-6597-0196

Funding

Linear Ion Trap - Quadrupole LC-MS SystemS10OD032292 · OD · WAYNE STATE UNIVERSITY · PI MADDIPATI, KRISHNARAO · 2022 to 2022
$592k
Triple Quadrupole - Ion Trap Hybrid LC/MS/MS SystemS10RR027926 · NCRR · WAYNE STATE UNIVERSITY · PI MADDIPATI, KRISHNARAO · 2010 to 2010
$425k
Exploring ovarian-derived hormone STC1 as the mediator of the protective effect of breast feeding against breast cancer.R21CA270702 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GERMAIN, DORIS A · 2023 to 2024
$423k
NCI NIH HHS R21 CA270702NCRR NIH HHS S10 RR027926NIH HHS S10 OD032292
6 · The paper itself

Abstract

Breastfeeding protects against breast cancer in some women but not others, however the mechanism remains elusive. Lactation requires intense secretory activity of the endoplasmic reticulum (ER) for the production of milk proteins and ER-mitochondria contacts for lipid synthesis. We show that in female mice that share the same nuclear genome (BL/6) but differ in mitochondrial genomes (

Identifiers

PMID38978600
PMCPMC11230499

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.