Evidence map›Paper›PMID 38979384›Full record

ArticlebioRxiv : the preprint server for biology2024

PKA Activity-Driven Modulation of Bidirectional Long-Distance transport of Lysosomal vesicles During Synapse Maintenance.

Kerriann K Badal, Yibo Zhao, Bindu L Raveendra, Sebastian Lozano-Villada, Kyle E Miller, Sathyanarayanan V Puthanveettil

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kerriann K BadalDepartment of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, FL 33458, USA.
Yibo ZhaoDepartment of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, FL 33458, USA.
Bindu L RaveendraDepartment of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, FL 33458, USA.
Sebastian Lozano-VilladaHarriet L. Wilkes Honors College, Florida Atlantic University, 5353 Parkside Drive, Jupiter, FL 33458, USA.
Kyle E MillerHarriet L. Wilkes Honors College, Florida Atlantic University, 5353 Parkside Drive, Jupiter, FL 33458, USA.
Sathyanarayanan V PuthanveettilDepartment of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, FL 33458, USA.

Funding

Dynein-Dynactin Complex Mediated Retrograde Transport during Long-term Memory StorageR01MH118444 · NIMH · UNIVERSITY OF FLORIDA · PI PUTHANVEETTIL, SATHYA · 2019 to 2023
$3.0M
Transcriptomic Mechanisms of Formation and Persistence of Synapse Specific Long-Term MemoryR01MH119541 · NIMH · UNIVERSITY OF FLORIDA · PI PUTHANVEETTIL, SATHYA · 2019 to 2023
$2.7M
The role of bidirectional transport of lysosome-related organelles in learning and memorystorageF31MH127958 · NIMH · UNIVERSITY OF FLORIDA · PI BADAL, KERRIANN · 2021 to 2023
$105k
NIMH NIH HHS F31 MH127958NIMH NIH HHS R01 MH118444NIMH NIH HHS R01 MH119541
6 · The paper itself

Abstract

The bidirectional long-distance transport of organelles is crucial for cell body-synapse communication. However, the mechanisms by which this transport is modulated for synapse formation, maintenance, and plasticity are not fully understood. Here, we demonstrate through quantitative analyses that maintaining sensory neuron-motor neuron synapses in the

Indexed as

gene expressionlong-distance transportlysosome related organellesmitochondriaplasticityProtein kinase ASynapse formationsynapse maintenance

Identifiers

PMID38979384
PMCPMC11230415

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.