ArticleBMJ (Clinical research ed.)2024
Reporting of surrogate endpoints in randomised controlled trial reports (CONSORT-Surrogate): extension checklist with explanation and elaboration.
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In one paragraph
Article in BMJ (Clinical research ed.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Proprioception Training and Surrogate Outcomes: A Systematic Review of Definitions, Measures, and Effectiveness Claims.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- CONSORT 2025 statement: updated guideline for reporting randomized trials: a Korean translation.Ewha medical journal · 2025Guideline
- Effects of aerobic training on cardiopulmonary fitness in patients with long COVID-19: a randomized controlled trial.Trials · 2024Trial
- Article
- Surrogate endpoints in cost-effectiveness analysis for use in health technology assessment - a qualitative analysis.International journal of technology assessment in health care · 2026Article
- Progression-Free Survival Effect Sizes in Randomized Controlled Trials of Targeted Cancer Therapies with Positive Outcomes.Acta haematologica · 2026Article
- More Than a Question of Correlation: Characterization of the Evidentiary Basis for Biomarker Surrogates Used in European Marketing Authorizations.Clinical pharmacology and therapeutics · 2026Review
- Preventing obesity-related cancer with the revolution in obesity management: the challenges of undertaking a clinical trial and potential solutions.British journal of cancer · 2026Review
- Survival and Surrogate Biomarkers in Interventional Oncology Trials: Pitfalls, Challenges, and Future Directions.Cardiovascular and interventional radiology · 2026Review
- Utilizing surrogate endpoints in clinical research: a strategic approach to overcome practical challenges.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2026Article
- Nanobiotic-Enhanced Probiotics for Targeted Gut Delivery: Mechanisms, Therapeutic Applications, and Translational Challenges.International journal of nanomedicine · 2026Review
- Patient and public involvement and engagement in methodology research: process, experiences, and recommendations from the SPIRIT- and CONSORT-Surrogate project.Research involvement and engagement · 2025Article
- Surrogate Outcomes Used as Proxies in Rare Long-Term Conditions: Evidence Assessment Group Perspective.PharmacoEconomics · 2025Article
- Recommended methodologies for clinical investigations of high-risk medical devices-Conclusions from the European Union CORE-MD Project.The Lancet regional health. Europe · 2025Review
- Use of surrogate endpoints in health technology assessment and reimbursement of treatments for the management of chronic kidney disease.EClinicalMedicine · 2025Review
- Role of prespecified analysis plans in physiological research: Encouraged or mandatory?Experimental physiology · 2025Article
- Developing, Analyzing, and Interpreting Outcome Assessments to Improve Endpoints in Infectious Diseases Clinical Research.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Article
- A call for transparency, improved reporting, and interpretation of trials using surrogate end points in cardiac electrophysiology.Heart rhythm · 2025Review
- Explanation & Elaboration document of the COSMIN Reporting Guideline 2.0 for studies on measurement properties of patient-reported outcome measures.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- CONSORT 2025 statement: updated guideline for reporting randomized trials.Nature medicine · 2025Review
Corrections and comments
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Authors and funding
36 authors.
Anthony Muchai ManyaraMRC/CSO Social and Public Health Sciences Unit, School of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Philippa DaviesPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Derek StewartPatient author, UK.
Christopher J WeirEdinburgh Clinical Trials Unit, Usher Institute, University of Edinburgh, Edinburgh, UK.
Amber E YoungPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Jane BlazebyPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Nancy J ButcherChild Health Evaluative Sciences, Hospital for Sick Children Research Institute, Toronto, ON, Canada.
Sylwia BujkiewiczBiostatistics Research Group, Department of Population Health Sciences, University of Leicester, Leicester, UK.
An-Wen ChanWomen's College Research Institute, Toronto, ON, Canada.
Dalia DawoudScience, Evidence, and Analytics Directorate, Science Policy and Research Programme, National Institute for Health and Care Excellence, London, UK.
Martin OffringaChild Health Evaluative Sciences, Hospital for Sick Children Research Institute, Toronto, ON, Canada.
Mario OuwensAstraZeneca, Mölndal, Sweden.
Asbjørn HróbjartssonCentre for Evidence-Based Medicine Odense and Cochrane Denmark, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Alain AmstutzCLEAR Methods Centre, Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel and University of Basel, Basel, Switzerland.
Luca BertolacciniDepartment of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Milan, Italy.
Vito Domenico BrunoIRCCS Galeazzi-Sant'Ambrogio Hospital, Department of Minimally Invasive Cardiac Surgery, Milan, Italy.
Declan DevaneUniversity of Galway, Galway, Ireland.
Christina D C M FariaDepartment of Physical Therapy, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Peter B GilbertFred Hutchinson Cancer Centre, Seattle, WA, USA.
Ray HarrisPatient author, UK.
Marissa LassereSt George Hospital and School of Population Health, University of New South Wales, Sydney, NSW, Australia.
Lucio MarinelliDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy.
Sarah MarkhamPatient author, UK.
John H PowersGeorge Washington University School of Medicine, Washington, DC, USA.
Yousef RezaeiHeart Valve Disease Research Centre, Rajaie Cardiovascular Medical and Research Centre, Iran University of Medical Sciences, Tehran, Iran.
Laura RichertUniversity of Bordeaux, Centre d'Investigation Clinique-Epidémiologie Clinique 1401, Research in Clinical Epidemiology and in Public Health and European Clinical Trials Platform & Development/French Clinical Research Infrastructure Network, Institut National de la Santé et de la Recherche Médicale/Institut Bergonié/Centre Hospitalier Universitaire Bordeaux, Bordeaux, France.
Falk SchwendickeCharité Universitätsmedizin Berlin, Berlin, Germany.
Larisa G TereshchenkoDepartment of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Achilles ThomaMcMaster University, Hamilton, ON, Canada.
Alparslan TuranDepartment of Outcomes Research, Anaesthesiology Institute, Cleveland Clinic, OH, USA.
Andrew WorrallPatient author, UK.
Robin ChristensenSection for Biostatistics and Evidence-Based Research, the Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen and Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark.
Gary S CollinsUK EQUATOR Centre, Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
Joseph S RossDepartment of Health Policy and Management, Yale School of Public Health, New Haven, CT, USA.
Rod S TaylorMRC/CSO Social and Public Health Sciences Unit, School of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Oriana CianiCentre for Research on Health and Social Care Management, Bocconi University, Milan 20136, Italy oriana.ciani@unibocconi.it.ORCID 0000-0002-3607-0508
Funding
American Heart Association-American Stroke Association 23IPA1054947American Heart Association-American Stroke Association 23TPA1141088Cancer Research UK 27294Medical Research Council MR/V038400/1
Abstract
PubMed holds no abstract for this paper.
Indexed as
BiomarkersChecklistRandomized Controlled Trials as TopicHumansResearch DesignBiomarkers
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What Socratic holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.